| Identification | Back Directory | [Name]
3-[3-[[[2-Chloro-3-(trifluoromethyl)phenyl]methyl](2,2-diphenylethyl)amino]propoxy]benzeneacetamide | [CAS]
405910-78-3 | [Synonyms]
GW6340 | [Molecular Formula]
C33H32ClF3N2O2 | [MOL File]
405910-78-3.mol | [Molecular Weight]
581.07 |
| Chemical Properties | Back Directory | [Boiling point ]
696.5±55.0 °C(Predicted) | [density ]
1.242±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(Predicted) | [form ]
Oil | [pka]
16.14±0.40(Predicted) | [color ]
Off-white to light yellow |
| Hazard Information | Back Directory | [Uses]
GW6340 is an intestinal-specific LXR agonist. GW6340 promotes macrophage reverse cholesterol transport (mRCT)[1]. | [References]
[1] Yasuda T, et al. Tissue-specific liver X receptor activation promotes macrophage reverse cholesterol transport in vivo. Arterioscler Thromb Vasc Biol. 2010 Apr;30(4):781-6. DOI:10.1161/ATVBAHA.109.195693 |
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Biorbyt Ltd.
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+44 (0)1223 859 353 |
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http://www.biorbyt.com |
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