| Identification | More | [Name]
4'-tert-Butyl-4-chlorobutyrophenone | [CAS]
43076-61-5 | [Synonyms]
4-CHLORO-1-[4-(1,1-DIMETHYLETHYL)PHENYL]-1-BUTANONE
4-Chloro-1-[4-(tert-butyl)phenyl]-1-butanone
4'-TERT-BUTYL-4-CHLOROBUTYROPHENONE
4-TERT-BUTYL-GAMMA-CHLOROBUTYROPHENONE
4-TERBUTYL-GAMMA-CHLOROBUTYROPHENONE
4-CHLORO-1-[4-(1,1-DIMETHYLPHENYL)PHENYL]-1-BUTANONE
4'-tert-Butyl-4-chlorobutyrophenone, 98+%
1-(4-tert-Butylphenyl)-4-chlorobutan-1-one
1-Butanone, 4-chloro-1-[4-(1,1-dimethylethyl)phenyl]- | [EINECS(EC#)]
256-077-8 | [Molecular Formula]
C14H19ClO | [MDL Number]
MFCD00018996 | [Molecular Weight]
238.75 | [MOL File]
43076-61-5.mol |
| Chemical Properties | Back Directory | [Appearance]
White to very slightly yellow powder | [Melting point ]
47-49 °C(lit.) | [Boiling point ]
152 °C (1 mmHg) | [density ]
1.0292 (rough estimate) | [refractive index ]
1.5260 (estimate) | [Fp ]
152-155°C/1mm | [storage temp. ]
Inert atmosphere,Room Temperature | [solubility ]
soluble in Methanol | [form ]
powder to crystal | [color ]
White to Light yellow | [BRN ]
780343 | [InChI]
InChI=1S/C14H19ClO/c1-14(2,3)12-8-6-11(7-9-12)13(16)5-4-10-15/h6-9H,4-5,10H2,1-3H3 | [InChIKey]
RLKSQLJFGCDUOX-UHFFFAOYSA-N | [SMILES]
C(C1=CC=C(C(C)(C)C)C=C1)(=O)CCCCl | [CAS DataBase Reference]
43076-61-5(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,N | [Risk Statements ]
R22:Harmful if swallowed.
R41:Risk of serious damage to eyes.
R43:May cause sensitization by skin contact.
R51/53:Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S61:Avoid release to the environment. Refer to special instructions safety data sheet .
S7/8:Keep container tightly closed and dry .
S24/25:Avoid contact with skin and eyes . | [RIDADR ]
UN 3077 9/PG 3
| [WGK Germany ]
2
| [REACH Registrations]
Active | [HS Code ]
2914790090 |
| Hazard Information | Back Directory | [Chemical Properties]
White to very slightly yellow powder | [Uses]
1-(4-tert-Butylphenyl)-4-chloro-1-butanone, is the starting material in the synthesis of Terfenadine (T114500). | [Synthesis]
In a dry reaction flask, add 4-chlorobutyrylbenzene, anhydrous aluminum trichloride, tert-butyl chloride, dichloromethane, stirring at 45 ℃ for 10 hours, after the reaction, the reaction solution is poured into a mixture of concentrated hydrochloric acid |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|