| Identification | More | [Name]
Methyl trifluoroacetate | [CAS]
431-47-0 | [Synonyms]
METHYL TRIFLUOROACETATE
TRIFLUOROACETIC ACID METHYL ESTER
Acetic acid, trifluoro-, methyl ester
trifluoro-aceticacimethylester
TFAME
Methyltrifluoroacetate,97%
Trifluoroacetic Acid Methyl Ether
Methyl trifluoroacetate 99%
2,2,2-TRIFLOUROMETHYLACETATE(TFAMT)
Methyltrifluoroacetate99%
Methyltrifluoracetat
Mthyl trifluoroacetate
Methyl trifluoroacetate, 98+%
Methyl 2,2,2-trifluoroacetate
Methyl perfluoroacetate | [EINECS(EC#)]
207-074-5 | [Molecular Formula]
C3H3F3O2 | [MDL Number]
MFCD00000417 | [Molecular Weight]
128.05 | [MOL File]
431-47-0.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless liquid | [Melting point ]
-78 °C
| [Boiling point ]
43-43.5 °C (lit.) | [density ]
1.273 g/mL at 25 °C(lit.)
| [vapor pressure ]
5.77 psi ( 20 °C)
| [refractive index ]
n20/D 1.291(lit.)
| [Fp ]
19 °F
| [storage temp. ]
0-6°C | [solubility ]
8g/l | [form ]
Liquid | [color ]
Clear colorless | [Specific Gravity]
1.273 | [PH]
7 (8g/l, H2O, 20℃) | [explosive limit]
6.1-24.8%(V) | [Water Solubility ]
8 g/L | [Sensitive ]
Moisture Sensitive | [BRN ]
1756070 | [Henry's Law Constant]
1.1×10-3 mol/(m3Pa) at 25℃, Burkholder et al. (2019) | [Dielectric constant]
11.460000000000001 | [Stability:]
Volatile | [InChI]
1S/C3H3F3O2/c1-8-2(7)3(4,5)6/h1H3 | [InChIKey]
VMVNZNXAVJHNDJ-UHFFFAOYSA-N | [SMILES]
COC(=O)C(F)(F)F | [LogP]
0.6 | [CAS DataBase Reference]
431-47-0(CAS DataBase Reference) | [NIST Chemistry Reference]
CF3C(O)OCH3(431-47-0) | [EPA Substance Registry System]
431-47-0(EPA Substance) |
| Safety Data | Back Directory | [Symbol(GHS) ]
 
GHS02,GHS05 | [Signal word ]
Danger | [Hazard statements ]
H225-H314 | [Precautionary statements ]
P210-P233-P240-P280-P303+P361+P353-P305+P351+P338 | [Hazard Codes ]
F,C | [Risk Statements ]
R11:Highly Flammable.
R34:Causes burns. | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2924 3/PG 2
| [WGK Germany ]
1
| [F ]
19 | [Hazard Note ]
Flammable/Corrosive | [TSCA ]
T | [REACH Registrations]
Active | [HazardClass ]
3 | [PackingGroup ]
II | [HS Code ]
29159080 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Flam. Liq. 2
Skin Corr. 1B |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless liquid | [Uses]
Methyl trifluoroacetate has been used as reagent for trifluoroacetylation of amines and amino acids. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 113, p. 700, 1991 DOI: 10.1021/ja00002a063 | [General Description]
Methyl trifluoroacetate along with cesium fluoride or cesium chloride and CuI constitutes a valuable trifluoromethylating reagent for substituting aromatic (or heteroaromatic) iodides and bromides. Adsorption of methyl trifluoroacetate on amorphous silica has been investigated. Fragmentation mechanism of generation of metastable ions from methyl trifluoroacetate has been investigated by mass analyzed ion kinetic energy spectra and ab initio molecular orbital calculations. | [Flammability and Explosibility]
Flammable |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
|