| Identification | More | [Name]
PHOSPHONOACETIC ACID | [CAS]
4408-78-0 | [Synonyms]
AURORA KA-1453
PHOSPHONOACETIC ACID
PHOSPHONOETHANOIC ACID
Carboxymethanephosphonic acid
carboxymethanephosphonicacid
Fosfonet
Fosfonoacetic acid
Phosphonacetic acid
phosphonaceticacid
phosphono-aceticaci
Phosphonoaceticacid,98+%
2-phosphonoacetic acid
Phosphonoacetate
Phosphonoethanoic acid, 98 %
(Carboxymethyl)phosphonic acid
(Dihydroxyphosphinyl)acetic acid
NSC-18205 | [EINECS(EC#)]
224-558-1 | [Molecular Formula]
C2H5O5P | [MDL Number]
MFCD00004311 | [Molecular Weight]
140.03 | [MOL File]
4408-78-0.mol |
| Chemical Properties | Back Directory | [Appearance]
White powder | [Melting point ]
143-146 °C (lit.) | [Boiling point ]
490.2±47.0 °C(Predicted) | [density ]
1.858±0.06 g/cm3(Predicted) | [refractive index ]
1.5180 (estimate) | [storage temp. ]
2-8°C | [solubility ]
water: soluble100mg/mL, clear to very slightly hazy, colorless | [form ]
Solid | [pka]
1.74±0.10(Predicted) | [color ]
White to off-white | [Water Solubility ]
Soluble in water. | [Sensitive ]
Hygroscopic | [BRN ]
1764355 | [CAS DataBase Reference]
4408-78-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [RIDADR ]
UN3261 | [WGK Germany ]
3
| [RTECS ]
AJ3278000
| [HazardClass ]
8 | [PackingGroup ]
III | [HS Code ]
29319019 |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
Phosphonoacetic acid was used as an inhibitor of viral DNA replication, to investigate the infected cell protein 0 (bICP0) localization in infected low passage bovine cells. It was also used as a phosphorus source for microbial growth in phosphate-independent manner. | [Uses]
Antiviral. | [Uses]
Phosphonoacetic acid inhibits deoxyribo nucleic acid polymerase, especially in viruses. It is used as an antiviral agent. Further, it is used in the preparation of 1-(dimethylamino)-2,2-bis[(dimethylimmonio)-methyl]ethene diperchlorate by reacting with phosphorus oxychloride. | [Definition]
ChEBI: A member of the class of phosphonic acids that is phosphonic acid in which the hydrogen attached to the phosphorous is replaced by a carboxymethyl group. | [IC 50]
Human Endogenous Metabolite | [storage]
Store at -20°C, sealed storage, away from moisture |
|
|