| Identification | More | [Name]
Cyclobutanemethanol | [CAS]
4415-82-1 | [Synonyms]
CYCLOBUTANECARBINOL
CYCLOBUTANEMETHANOL
cyclobutylcarbinol
CYCLOBUTYLMETHANOL
(HYDROXYMETHYL)CYCLOBUTANE
RARECHEM AK ML 0579
Cyclobutylcarbinol~Hydroxymethylcyclobutane
Cyclobutanemethanol,99%
Cyclobutylmethyl alcohol
Cyclobutane-1-methanol | [EINECS(EC#)]
224-575-4 | [Molecular Formula]
C5H10O | [MDL Number]
MFCD00001330 | [Molecular Weight]
86.13 | [MOL File]
4415-82-1.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear colourless liquid | [Melting point ]
68.5 °C | [Boiling point ]
143-144 °C(lit.) | [density ]
0.913 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.446(lit.)
| [Fp ]
104 °F
| [storage temp. ]
Flammables area | [form ]
Liquid | [pka]
15.26±0.10(Predicted) | [color ]
Clear colorless | [Water Solubility ]
immiscible | [BRN ]
2036027 | [InChIKey]
WPOPOPFNZYPKAV-UHFFFAOYSA-N | [CAS DataBase Reference]
4415-82-1(CAS DataBase Reference) | [NIST Chemistry Reference]
Cyclobutanemethanol(4415-82-1) |
| Safety Data | Back Directory | [Risk Statements ]
R10:Flammable. | [Safety Statements ]
S16:Keep away from sources of ignition-No smoking . | [RIDADR ]
UN 1987 3/PG 3
| [WGK Germany ]
3
| [HazardClass ]
3 | [PackingGroup ]
III | [HS Code ]
29061900 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear colourless liquid | [Uses]
Cyclobutanemethanol was used in the synthesis of bicyclic lactone. | [Application]
Cyclobutanemethanol is a drug used to treat inflammatory diseases. It is an uptake inhibitor that blocks the transport of uridine into cells, preventing the activation of G-protein coupled receptors and the subsequent production of inflammatory mediators. Cyclobutanemethanol has been shown to have anti-inflammatory properties by inhibiting the CB2 receptor, which is found in large quantities in inflammatory tissues. It also prevents dehydration and increases blood flow to inflamed areas by acting on vascular endothelial cells. It has been shown to inhibit influenza virus replication in vitro, but not in vivo. | [General Description]
Oxidation of cyclobutanemethanol in the presence of lead tetraacetate and lead tetraacetate/metal chloride has been investigated. | [Synthesis]
Cyclobutanemethanol can be synthesized from two molecules of hydrochloric acid and one molecule of cyclobutane. The synthesis pathway includes removal of a hydroxy group and addition of an alkynyl group via hydrogen bonding interactions with chloride ions. |
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