ChemicalBook--->CAS DataBase List--->444287-40-5

444287-40-5

444287-40-5 Structure

444287-40-5 Structure
IdentificationBack Directory
[Name]

1H-Isoindole-1,3(2H)-dione, 4-(aminomethyl)-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)
[CAS]

444287-40-5
[Synonyms]

4-(Aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride
1H-Isoindole-1,3(2H)-dione, 4-(aminomethyl)-2-(2,6-dioxo-3-piperidinyl) hydrochloride
1H-Isoindole-1,3(2H)-dione,4-(aminomethyl)-2-(2,6-dioxo-3-piperidinyl)-, monohydrochloride
1H-Isoindole-1,3(2H)-dione, 4-(aminomethyl)-2-(2,6-dioxo-3-piperidinyl)-, hydrochloride (1:1)
[Molecular Formula]

C14H14ClN3O4
[MDL Number]

MFCD32183715
[MOL File]

444287-40-5.mol
[Molecular Weight]

323.73
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[form ]

powder
[InChI]

1S/C14H13N3O4/c15-6-7-2-1-3-8-11(7)14(21)17(13(8)20)9-4-5-10(18)16-12(9)19/h1-3,9H,4-6,15H2,(H,16,18,19)
[InChIKey]

TUMJPYMYNBEMDD-UHFFFAOYSA-N
[SMILES]

NCC1=C(C(N(C2CCC(NC2=O)=O)C3=O)=O)C3=CC=C1
Safety DataBack Directory
[WGK Germany ]

WGK 3
[Storage Class]

6.1C - Combustible acute toxic Cat.3
toxic compounds or compounds which causing chronic effects
[Hazard Classifications]

Repr. 1B
Hazard InformationBack Directory
[Uses]

4-Aminomethyl-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione hydrochloride is a functionalized Cereblon ligand used for development of protein degrader building blocks. Contains a terminal amine group, allowing rapid conjugation of carboxyl containing linkers. A basic building block for development of a protein degrader library.
[reaction suitability]

reagent type: ligand
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