ChemicalBook--->CAS DataBase List--->4637-24-5

4637-24-5

4637-24-5 Structure

4637-24-5 Structure
IdentificationMore
[Name]

N,N-Dimethylformamide dimethyl acetal
[CAS]

4637-24-5
[Synonyms]

1,1-DIMETHOXY-N,N-DIMETHYL METHANAMINE
1,1-DIMETHOXY-N,N-DIMETHYLMETHYLAMINE
1,1-DIMETHOXYTRIMETHYLAMINE
AURORA KA-683
DIMETHYLFORMAMIDEDIMETHYLACETAL
DMF-DIMETHYLACETAL
DMF-DMA
METHYL-8
METHYL-8 REAGENT
METHYL-8(R) REAGENT
N-DIMETHOXYMETHYL-N,N-DIMETHYLAMINE
N,N-DIMETHYLDIMETHOXYMETHYLAMINE
N,N-DIMETHYLFORMAMIDE DIMETHYL ACETAL
1,1-dimethoxy-n,n-dimethyl-methanamin
Dimethoxy(dimethylamino)methane
Dimethoxy-N,N-dimethylmethanamine
N-(Dimethoxymethyl)dimethylamine
N,N-Dimethylfirmanmidedimethylacetal
Trimethylamine, 1,1-dimethoxy-
DMFDMA (DMFA)
[EINECS(EC#)]

225-063-3
[Molecular Formula]

C5H13NO2
[MDL Number]

MFCD00008482
[Molecular Weight]

119.16
[MOL File]

4637-24-5.mol
Chemical PropertiesBack Directory
[Appearance]

clear colourless liquid
[Melting point ]

-85°C
[Boiling point ]

102-103 °C/720 mmHg (lit.)
[density ]

0.897 g/mL at 25 °C(lit.)
[vapor pressure ]

34.5hPa at 20℃
[refractive index ]

n20/D 1.396(lit.)
[Fp ]

45 °F
[storage temp. ]

Flammables area
[solubility ]

Miscible with most organic solvents.
[form ]

Solid
[pka]

5.00±0.50(Predicted)
[color ]

White to off-white
[PH]

7 (H2O)
[explosive limit]

1.3-17.7%(V)
[Water Solubility ]

hydrolysis
[Sensitive ]

Moisture Sensitive
[Detection Methods]

GC,NMR
[BRN ]

506020
[Exposure limits]

ACGIH: TWA 200 ppm; STEL 250 ppm (Skin)
OSHA: TWA 200 ppm(260 mg/m3)
NIOSH: IDLH 6000 ppm; TWA 200 ppm(260 mg/m3); STEL 250 ppm(325 mg/m3)
[LogP]

0.750 (est)
[CAS DataBase Reference]

4637-24-5(CAS DataBase Reference)
[NIST Chemistry Reference]

Methanamine, 1,1-dimethoxy-N,N-dimethyl-(4637-24-5)
[Storage Precautions]

Moisture sensitive
[EPA Substance Registry System]

4637-24-5(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

F,Xn,Xi
[Risk Statements ]

R11:Highly Flammable.
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin .
R36/38:Irritating to eyes and skin .
R20:Harmful by inhalation.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R10:Flammable.
[Safety Statements ]

S16:Keep away from sources of ignition-No smoking .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37:Wear suitable protective clothing and gloves .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S33:Take precautionary measures against static discharges .
S29:Do not empty into drains .
S7/9:Keep container tightly closed and in a well-ventilated place .
[RIDADR ]

UN 3271 3/PG 2
[WGK Germany ]

1
[F ]

21
[Autoignition Temperature]

155 °C
[TSCA ]

Yes
[HazardClass ]

3
[PackingGroup ]

II
[HS Code ]

29225000
[Toxicity]

LD50 orally in Rabbit: > 5000 mg/kg
Raw materials And Preparation ProductsBack Directory
[Preparation Products]

5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-AMINE-->[1-(4-FLUOROPHENYL)-5-METHYL-1H-PYRAZOL-4-YL]METHANOL-->1-TERT-BUTYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-4-AMINE-->METHYL 4-AMINO-6-INDOLECARBOXYLATE-->Indole-6-carboxylic acid-->2-AMINO-4-METHYL-PYRIMIDINE-5-CARBOXYLIC ACID-->1-METHYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID-->3-BROMOCHROMONE-->3-NITROISONICOTINALDEHYDE-->5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBONITRILE-->ETHYL 2-METHYL-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLATE-->ETHYL 1-(4-FLUOROPHENYL)-5-METHYL-1H-PYRAZOLE-4-CARBOXYLATE-->5-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOLE-4-CARBONITRILE-->1-TERT-BUTYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBONITRILE-->(5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-YL)METHANAMINE-->5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBONYL CHLORIDE-->(1-TERT-BUTYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-4-YL)METHANAMINE-->1-TERT-BUTYL 6-METHYL 3-FORMYL-1H-INDOLE-1,6-DICARBOXYLATE-->(5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOL-4-YL)METHANOL-->5-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOLE-4-CARBOXAMIDE-->(5-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOL-4-YL)METHANOL-->Indole-7-carboxaldehyde-->(1-TERT-BUTYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOL-4-YL)METHANOL-->5-(TRIFLUOROMETHYL)-1-METHYL-1H-PYRAZOLE-4-CARBOXAMIDE-->1-PHENYL-5-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBONYL CHLORIDE-->Indole-6-carboxaldehyde-->(5-(TRIFLUOROMETHYL)-1-PHENYL-1H-PYRAZOL-4-YL)METHANAMINE-->3-NITROBENZO[B]FURAN-5-OL-->ETHYL 2-PHENYL-3-(TRIFLUOROMETHYL)PYRAZOLE-4-CARBOXYLATE-->6-HYDROXYMETHYLINDOLE-->ETHYL 1-(TERT-BUTYL)-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLATE-->4-(Pyridin-3-yl)pyrimidin-2-amine-->4-Aminomethyl-1-methylpyrazole-->1-PHENYL-5-(TRIFLUOROMETHYL)-1H-PYRAZOLE-4-CARBOXYLIC ACID-->5-Hydroxyindole-->7-Hydroxyindole
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

N-Dimethoxymethyl-N,N-dimethylamine(4637-24-5).msds
Hazard InformationBack Directory
[Chemical Properties]

clear colourless liquid
[Uses]

1,1-Dimethoxy-N,N-dimethylmethanamine is used as a reagent in the formation of pyridine derivatives that exhibit inhibition against PI3 kinase p110α enzymes.
[Definition]

ChEBI: An acetal obtained by formal condensation of N,N-dimethylformamide with methanol. N,N-dimethylformamide dimethyl acetal is a derivatisation agent used in gas-chromatography applica ions
[General Description]

Esterate M (N,N-Dimethylformamide dimethyl acetal, DMFDMA) is an methylating reagent. It has been used in methyl esterification of carboxylic acid and also in one-step derivatization of amino acids into N,N-Dimethylaminomethylene methyl esters.
[Flammability and Explosibility]

Highlyflammable
Spectrum DetailBack Directory
[Spectrum Detail]

N,N-Dimethylformamide dimethyl acetal(4637-24-5)1HNMR
N,N-Dimethylformamide dimethyl acetal(4637-24-5)IR1
N,N-Dimethylformamide dimethyl acetal(4637-24-5)Raman
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

N,N-Dimethylformamide dimethyl acetal, ca 97%(4637-24-5)
[Alfa Aesar]

N,N-Dimethylformamide dimethyl acetal, 97%(4637-24-5)
[Sigma Aldrich]

4637-24-5(sigmaaldrich)
[TCI AMERICA]

N,N-Dimethylformamide Dimethyl Acetal,>95.0%(GC)(4637-24-5)
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