| Identification | Back Directory | [Name]
3-(4-CHLORO-PHENYL)-QUINOXALINE-5-CARBOXYLIC ACID AMIDE | [CAS]
489457-67-2 | [Synonyms]
3-(4-Chlorophenyl)quinoxaline-5-carboxamide
3-(4-CHLORO-PHENYL)-QUINOXALINE-5-CARBOXYLIC ACID AMIDE | [Molecular Formula]
C15H10ClN3O | [MDL Number]
MFCD11856053 | [MOL File]
489457-67-2.mol | [Molecular Weight]
283.717 |
| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [solubility ]
DMSO: 10mg/mL | [form ]
Light brown solid. | [color ]
light brown | [InChI]
1S/C15H10ClN3O/c16-10-6-4-9(5-7-10)13-8-18-12-3-1-2-11(15(17)20)14(12)19-13/h1-8H,(H2,17,20) | [InChIKey]
FLYGLPYJEQPCFY-UHFFFAOYSA-N | [SMILES]
Clc1ccc(cc1)c2nc3c(nc2)cccc3C(=O)N |
| Hazard Information | Back Directory | [Uses]
A potent quinoxaline-based PARP inhibitor with a ~5-fold selectivity towards PARP-2 over PARP-1 (IC50 = 7 and 33 nM, respectively). Reported to be brain-permeant and exhibit good pharmacokinetics. |
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| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|