| Identification | More | [Name]
Chloromethyl chlorosulfate | [CAS]
49715-04-0 | [Synonyms]
CHLOROMETHYL CHLOROSULFATE
chloromethyl chlorosulphate
CHLOROMETHYL CHLOROSULPHATE (CMCS)
Chloro chloromethyl sulfate
Chlorosulfuric acid, chloromethyl ester
3HLOROMETHYL CHLOROSULFATE, 98%
Chloridosulfuric acid (chloromethyl) ester
Chloridosulfuric acid chloromethyl ester | [EINECS(EC#)]
256-442-1 | [Molecular Formula]
CH2Cl2O3S | [MDL Number]
MFCD00041547 | [Molecular Weight]
165 | [MOL File]
49715-04-0.mol |
| Chemical Properties | Back Directory | [Appearance]
Clear colourless to yellow liquid | [Boiling point ]
45-50 °C/10 mmHg | [density ]
1.631 g/mL at 25 °C
| [refractive index ]
n 20/D 1.448
| [Fp ]
176 °F
| [storage temp. ]
Store at 2-8C | [solubility ]
soluble in Chloroform, Ethyl Acetate | [form ]
Liquid | [color ]
Clear colorless to yellow | [Water Solubility ]
reacts | [Stability:]
Moisture Sensitive | [InChI]
InChI=1S/CH2Cl2O3S/c2-1-6-7(3,4)5/h1H2 | [InChIKey]
PJBIHXWYDMFGCV-UHFFFAOYSA-N | [SMILES]
S(Cl)(OCCl)(=O)=O | [CAS DataBase Reference]
49715-04-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
C,T+ | [Risk Statements ]
R22:Harmful if swallowed.
R34:Causes burns.
R26:Very Toxic by inhalation. | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 1760 8/PG 3
| [WGK Germany ]
3
| [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29049090 |
| Hazard Information | Back Directory | [Chemical Properties]
Clear colourless to yellow liquid | [Uses]
Reagent for chloromethylation of Fmoc-protected amino acids without the generation of carcinogenic bis(chloromethyl)ether. | [Synthesis]
1) reacting liquid sulfur trioxide with methylene chloride for 1 to 24 hours at -50 to 40° C. in the presence of a catalyst carbonate, a saturated hydrocarbon base carbonate containing saturated hydrocarbon base, a borate salt, and a borate containing sat |
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