| Identification | More | [Name]
Ethyl malonyl chloride | [CAS]
36239-09-5 | [Synonyms]
AURORA KA-3051
(CHLOROFORMYL)ACETIC ACID ETHYL ESTER
ETHYL 2-(CHLOROCARBONYL)ACETATE
ETHYL 3-CHLORO-3-OXOPROPIONATE
ETHYL (CHLOROFORMYL)ACETATE
ETHYL MALONYL CHLORIDE
MALONIC ACID MONOETHYL ESTER CHLORIDE
3-chloro-3-oxo-propanoicaciethylester
Propanoic acid, 3-chloro-3-oxo-, ethyl ester
Ethyl 3-chloro-3-oxopropionate, Ethyl (chloroformyl)acetate
ETHYL 3-CHLORO-3-OXOPROPIONATE,TECH
Ethyl Maloriyl Chloride
Ethyl malonyl chloride, pract., 90+%
Ethylmalonylchloride,95%
Ethyl malonyl chloride, tech., 90%
ETHYLMALONYLCHLORIDE,TECHNICAL
Ethyl (chloroformyl)acetate, Ethyl 3-chloro-3-oxopropionate
2-(Ethoxycarbonyl)acetyl chloride
Acetic acid, (chloroformyl)-, ethyl ester
Carbethoxyethanoyl chloride | [EINECS(EC#)]
252-934-5 | [Molecular Formula]
C5H6Cl2O2 | [MDL Number]
MFCD00000736 | [Molecular Weight]
169.01 | [MOL File]
36239-09-5.mol |
| Chemical Properties | Back Directory | [Appearance]
clear yellow to brown liquid | [Boiling point ]
79-80 °C25 mm Hg(lit.) | [density ]
1.196 g/mL at 20 °C
| [refractive index ]
n20/D 1.429(lit.)
| [Fp ]
154 °F
| [storage temp. ]
2-8°C
| [solubility ]
Chloroform (Soluble), DMSO (Sparingly), Ethyl Acetate (Slightly) | [form ]
Liquid | [pka]
9.35±0.46(Predicted) | [color ]
Clear yellow to brown | [Specific Gravity]
1.176 | [Water Solubility ]
REACTS | [Sensitive ]
Moisture Sensitive | [BRN ]
636215 | [Stability:]
Hygroscopic, Moisture Sensitive | [InChI]
1S/C5H7ClO3/c1-2-9-5(8)3-4(6)7/h2-3H2,1H3 | [InChIKey]
KWFADUNOPOSMIJ-UHFFFAOYSA-N | [SMILES]
CCOC(=O)CC(Cl)=O | [CAS DataBase Reference]
36239-09-5(CAS DataBase Reference) | [NIST Chemistry Reference]
Ethyl malonyl chloride(36239-09-5) | [Storage Precautions]
Moisture sensitive;Store under inert gas |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS05 | [Signal word ]
Danger | [Hazard statements ]
H314 | [Precautionary statements ]
P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363-P405 | [Hazard Codes ]
C | [Risk Statements ]
R14:Reacts violently with water.
R34:Causes burns. | [Safety Statements ]
S7:Keep container tightly closed .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S36/39:Wear suitable protective clothing and eye/face protection . | [RIDADR ]
UN 3265 8/PG 3
| [WGK Germany ]
3
| [F ]
10-21 | [Hazard Note ]
Corrosive | [REACH Registrations]
Active | [HazardClass ]
8 | [PackingGroup ]
II | [HS Code ]
29171900 | [Storage Class]
8A - Combustible corrosive hazardous materials | [Hazard Classifications]
Skin Corr. 1B |
| Raw materials And Preparation Products | Back Directory | [Preparation Products]
7-Fluoro-3,4-dihydro-6-nitro-3-oxoquinoxaline-2-carboxylic acid-->2,3,4,5-Tetrahydro-5-methyl-1H-pyrido[4,3-b]indol-1-one-->5,6-Dihydro-4-(2-methyl-2-phenylhydrazino)-2-1H-pyridinone-->2,4-Piperadinedione-->tert-Butyl ethyl malonate-->4-Pyridazinecarboxylic acid, 2,3-dihydro-5-hydroxy-2-(3-methylbutyl)-3-oxo-6-(2-thienyl)-, ethyl ester-->ethyl 3-[(5-chloro-2-nitrophenyl)phenylamino]-3-oxopropionate |
| Hazard Information | Back Directory | [Chemical Properties]
clear yellow to brown liquid | [Uses]
Employed in the synthesis of 3-pyrrolin-2-ones via amidation with propargylamines and subsequent base catalyzed 5-exo-dig cyclization.1 | [Uses]
Ethyl malonyl chloride is used in the syntheses of methanofullerodendimers and 3-pyrrolin-2-ones. It plays a vital role in the preparation of 3,5-disubstituted 1,2,4-oxadiazole derivatives, which are potential peptidomimetic building blocks. It is a versatile acylating agent for propargyl alcohols, hydrazines and amines. | [General Description]
Ethyl malonyl chloride is a versatile acylating agent for propargyl alcohols, hydrazines and amines. | [Synthesis]
Method I. Ethyl chloroformylacetate, also known as ethyl 3-chloro-3-oxopropionate, ethyl malonate monochloride, can be obtained by chlorination of 3-ethoxy-3-oxopropionic acid, and the chlorination reagent can be selected from sulfoxide chloride and ox |
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J & K SCIENTIFIC LTD.
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18210857532 18210857532 |
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https://www.jkchemical.com |
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Alfa Aesar
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400-6106006 |
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http://chemicals.thermofisher.cn |
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Energy Chemical
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400-0056266 |
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www.energy-chemical.com |
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Jia Xing Isenchem Co.,Ltd
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0573-85285100 18627885956 |
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