| Identification | Back Directory | [Name]
3-[(4-Cyanophenyl)methyl]-N-(3-methyl-5-isothiazolyl)-alpha-oxo-1-indolizineacetamide | [CAS]
501948-05-6 | [Synonyms]
STA 5312
Rosabulin
3-[(4-cyanophenyl)methyl]-N-(3-methyl-5-isothiazolyl)-α-oxo-1-indolizineacetamide
1-Indolizineacetamide, 3-[(4-cyanophenyl)methyl]-N-(3-methyl-5-isothiazolyl)-α-oxo-
3-[(4-Cyanophenyl)methyl]-N-(3-methyl-5-isothiazolyl)-alpha-oxo-1-indolizineacetamide | [Molecular Formula]
C22H16N4O2S | [MDL Number]
MFCD13152388 | [MOL File]
501948-05-6.mol | [Molecular Weight]
400.45 |
| Chemical Properties | Back Directory | [Melting point ]
233 ºC | [density ]
1.34 | [storage temp. ]
Store at -20°C | [solubility ]
Soluble in DMSO | [form ]
Solid | [pka]
8.00±0.46(Predicted) | [color ]
Light yellow to green yellow |
| Hazard Information | Back Directory | [Uses]
Treatment of therapeutic resistant cancers. | [in vivo]
When dosed orally or intravenously, Rosabulin (STA 5312) has shown in vivo activity in several murine tumors as well as human tumor xenograft models, including drug resistant tumors[1]. | [storage]
Store at -20°C |
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