| Identification | More | [Name]
Ethyl trichloroacetate | [CAS]
515-84-4 | [Synonyms]
ETHYL TRICHLOROACETATE
RARECHEM AL BI 1451
TRICHLOROACETATE ETHYL ESTER
TRICHLOROACETIC ACID ETHYL ESTER
Acetic acid, 2,2,2-trichloroethyl ester
Acetic acid, ester with trichloroethanol
ethanoicacid,trichloro-,ethylester
ethyltrichloracetate
trichloro-aceticaciethylester
Trichloroethyl acetate
ETHYL TRICHLOROACETATE 98% (GC)
ETHYL TRICHLOROACETATE PESTANAL, 250 MG
Ethyl trichloroacetate, stabilized, 97%
Acetic acid, trichloro-, ethyl ester
Ethyltrichloracetat
ETHYL TRICHLOROACETATE , STABILIZED WITH EPOXY RESIN
ETHYL TRICHLOROACETATE, STABILSED WITH EPOXY RESIN
Ethyl trichloroacetate, 97%, stab. with epoxy resin
Ethyl 2,2,2-trichloroacetate
Ethyl trichloroacetate, 97%, stabilized | [EINECS(EC#)]
208-212-7 | [Molecular Formula]
C4H5Cl3O2 | [MDL Number]
MFCD00000795 | [Molecular Weight]
191.44 | [MOL File]
515-84-4.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless liquid | [Melting point ]
237 °C | [Boiling point ]
168 °C (lit.) | [density ]
1.378 g/mL at 25 °C(lit.)
| [vapor pressure ]
2.34hPa at 25℃ | [refractive index ]
n20/D 1.453(lit.)
| [Fp ]
149 °F
| [storage temp. ]
Store below +30°C. | [solubility ]
alcohol: miscible(lit.) | [form ]
clear liquid | [color ]
Colorless to Almost colorless | [Water Solubility ]
immiscible | [Merck ]
9627 | [BRN ]
1761567 | [Dielectric constant]
7.8（20℃） | [InChI]
1S/C4H5Cl3O2/c1-2-9-3(8)4(5,6)7/h2H2,1H3 | [InChIKey]
SJMLNDPIJZBEKY-UHFFFAOYSA-N | [SMILES]
CCOC(=O)C(Cl)(Cl)Cl | [LogP]
2.22 at 25℃ | [CAS DataBase Reference]
515-84-4(CAS DataBase Reference) | [NIST Chemistry Reference]
Acetic acid, trichloro-, ethyl ester(515-84-4) | [EPA Substance Registry System]
515-84-4(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [RIDADR ]
2810 | [WGK Germany ]
1
| [TSCA ]
TSCA listed | [HS Code ]
29154000 | [Storage Class]
10 - Combustible liquids | [Hazard Classifications]
Acute Tox. 4 Oral
Skin Irrit. 2 |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless liquid | [Uses]
Ethyl trichloroacetate was used in the synthesis of dichlorocarbon precursor, phenyl(trichloromethyl)methyl. | [Application]
Ethyl trichloroacetate can be used as solvent, organic synthesis, perfume and pharmaceutical intermediates. | [Preparation]
Ethyl trichloroacetate was synthesized by esterification of trichloroacetic acid with ethanol.
Trichloroacetic acid(TCA), anhydrous ethanol and sulfuric acid are heated together and refluxed for 6 h. After cooling, the ester layer is separated by pouring into water, neutralized with 5-10% sodium carbonate solution, washed with water and dried overnight with anhydrous calcium chloride. After filtration, distillation was carried out to obtain the finished product of ethyl trichloroacetate. Yield 75%. | [Synthesis Reference(s)]
The Journal of Organic Chemistry, 46, p. 3519, 1981 DOI: 10.1021/jo00330a028 | [General Description]
Ethyl trichloroacetate undergoes atom-transfer radical addition reaction with styrene catalyzed by the Ru-pentamethylcyclopentadienyl complexes. | [Purification Methods]
Shake the ester with saturated aqueous Na2CO3 (three times), aqueous 50% CaCl2 (three times), saturated aqueous NaCl (twice), then distil over CaCl2 and redistil it under reduced pressure. [Beilstein 2 IV 514.] |
|
|