ChemicalBook--->CAS DataBase List--->5222-73-1

5222-73-1

5222-73-1 Structure

5222-73-1 Structure
IdentificationMore
[Name]

3,4-Dimethoxy-3-cyclobutene-1,2-dione
[CAS]

5222-73-1
[Synonyms]

3,4-DIMETHOXY-3-CYCLOBUTENE-1,2-DIONE
3,4-DIMETHOXYCYCLOBUT-3-ENE-1,2-DIONE
DIMETHYL SQUARATE
SQUARIC ACID
SQUARIC ACID DIMETHYL ESTER
3-Cyclobutene-1,2-dione,3,4-dimethoxy-
3,4-DIMETHOXY-3-CYCLOBUTENE-1,2-DIONE, 9 9%
Squaric acid dimethyl ester,(Dimethyl squarate, 3,4-Dimethoxy-3-cyclobutene-1,2-dione)
3,4-DIMETHOXYCYCLOBUTANE-1,2-DIONE
Dimethyl squarate, Squaric acid dimethyl ester
1,2-Dimethoxy-1-cyclobutene-3,4-dione
1,2-Dimethoxycyclobutene-3,4-dione
[EINECS(EC#)]

220-761-4
[Molecular Formula]

C6H6O4
[MDL Number]

MFCD00101316
[Molecular Weight]

142.11
[MOL File]

5222-73-1.mol
Chemical PropertiesBack Directory
[Appearance]

white crystalline powder
[Melting point ]

55-57 °C (lit.)
[Boiling point ]

219.65°C (rough estimate)
[density ]

1.3863 (rough estimate)
[refractive index ]

1.5800 (estimate)
[storage temp. ]

0-6°C
[Water Solubility ]

Very soluble in water.
[InChIKey]

SZBNZTGCAMLMJY-UHFFFAOYSA-N
[CAS DataBase Reference]

5222-73-1(CAS DataBase Reference)
[NIST Chemistry Reference]

3,4-Dimethoxy-3-cyclobutene-1,2-dione(5222-73-1)
Safety DataBack Directory
[Risk Statements ]

R42/43:May cause sensitization by inhalation and skin contact .
[Safety Statements ]

S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
[WGK Germany ]

3
[HS Code ]

29145090
Hazard InformationBack Directory
[Chemical Properties]

white crystalline powder
[Uses]

3,4-Dimethoxy-3-cyclobutene-1,2-dione (Dimethyl squarate) finds it uses in the synthesis of chiral squaramides, highly enantioselective catalyst for the Friedel-Crafts reactions of indoles, 3-(hydroxyamino)-4-methoxy-3-cyclobutene-1,2-dione, squarate derivatives of the O-SP-core antigens, methyl squarate derivative of the Ogawa O-SP-core antigen, o-quinodimethanes, benzocyclobutenes, quinones. It is employed as a starting material in the preparation of o-quinodimethanes, benzocyclobutenes, and quinones.
[General Description]

3,4-Dimethoxy-3-cyclobutene-1,2-dione (Dimethyl squarate) is a cyclobutene derivative. It reacts with hydroxylamine derivatives to afford 3-hydroxyamino-4-methoxy-3-cyclobutene-1,2-diones.
Spectrum DetailBack Directory
[Spectrum Detail]

3,4-Dimethoxy-3-cyclobutene-1,2-dione(5222-73-1)MS
3,4-Dimethoxy-3-cyclobutene-1,2-dione(5222-73-1)1HNMR
3,4-Dimethoxy-3-cyclobutene-1,2-dione(5222-73-1)13CNMR
3,4-Dimethoxy-3-cyclobutene-1,2-dione(5222-73-1)IR1
3,4-Dimethoxy-3-cyclobutene-1,2-dione(5222-73-1)IR2
Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

3,4-Dimethoxy-3-cyclobutene-1,2-dione, 99%(5222-73-1)
[Alfa Aesar]

3,4-Dimethoxy-3-cyclobutene-1,2-dione, 98%(5222-73-1)
[Sigma Aldrich]

5222-73-1(sigmaaldrich)
[TCI AMERICA]

3,4-Dimethoxy-3-cyclobutene-1,2-dione,>98.0%(GC)(5222-73-1)
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