| Identification | More | [Name]
Dazomet | [CAS]
533-74-4 | [Synonyms]
2-thio-3,5-dimethyl-tetrahydro-1,3,5-thiadiazine
3,5-Dimethyl-1,2,3,5-tetrahydro-1,3,5-thiadiazinethione-2
3,5-dimethyltetrahydro-1,3,5-thiadiazine-2-thione
BASAMID
BASAMID(R)
BIOCIDE N521(R)
CRAGE FUNGICIDE 974(R)
DAZOBERG
DAZOMET
Dazomet(content>25%)
DMTT
DMTT(R)
MYLONE(R)
PRESERVIT(R)
TETRAHYDRO-3,5-DIMETHYL-2H-1,3,5-THIADIAZINE-2-THIONE
3,5-Dimethyl tetrahydro-2-H,1,3,5-thiadiazone-2-thione
3,5-Dimethyl-1,3,5-2H-tetrahydrothiadiazine-2-thione
3,5-Dimethyl-1,3,5-thiadiazinane-2-thione
3,5-Dimethyl-2-thionotetrahydro-1,3,5-thiadiazine
3,5-Dimethylperhydro-1,3,5-thiadiazin-2-thion | [EINECS(EC#)]
208-576-7 | [Molecular Formula]
C5H10N2S2 | [MDL Number]
MFCD00023809 | [Molecular Weight]
162.28 | [MOL File]
533-74-4.mol |
| Chemical Properties | Back Directory | [Appearance]
White crystalline solid. Nearly odorless. | [Melting point ]
104-105°C | [Boiling point ]
222.3±50.0 °C(Predicted) | [density ]
1.3 | [vapor pressure ]
3.7 x 10-4 Pa (25 °C) | [refractive index ]
1.5005 (estimate) | [Fp ]
156 °C | [storage temp. ]
0-6°C | [solubility ]
Chloroform (Slightly), DMSO (Slightly) | [form ]
neat | [pka]
4.04±0.20(Predicted) | [Water Solubility ]
<0.1 g/100 mL at 18 ºC | [Merck ]
13,2854 | [BRN ]
116039 | [Contact allergens]
Dazomet is a biocide used to control bacterial and fungal growth in a pulp and paper system, and also in agriculture for soil disinfection. It is contained in Busan 1058, Mylone, and Fungicide 974 (Crag™). Sensitization, rarely reported, occurred in a paper mill worker. | [InChIKey]
QAYICIQNSGETAS-UHFFFAOYSA-N | [LogP]
1.400 | [CAS DataBase Reference]
533-74-4(CAS DataBase Reference) | [NIST Chemistry Reference]
2H-1,3,5-thiadiazine-2-thione, tetrahydro-3,5-dimethyl-(533-74-4) | [EPA Substance Registry System]
533-74-4(EPA Substance) |
| Hazard Information | Back Directory | [Uses]
Dazomet is a as fumigant used for the control of brown root rot disease. Dazomet was shown to be a possible agent in preventing pest incursion in agriculture, gardening and agroforestry. | [Definition]
ChEBI: A dithiocarbamic ester that is 1,3,5-thiadiazinane with a thione moiety at position 2 and in which the hydrogens attached to the nitrogens are replaced by methyl groups. A fungicide, herbicide and nematicide, it is used prior to sowing or planting for the
ontrol of soil fungi, nematodes, bacteria and germinating weeds, and as fumigant for poultry litter and eggs to control Salmonella. It is a non-ozone-depleting alternative to methyl bromide. | [Uses]
Soil fungicide, nematocide, weed killer; slimicide in paper making. | [General Description]
White crystals or off-white powder. Pungent, acrid odor. | [Reactivity Profile]
DAZOMET(533-74-4) decomposes in water, dilute acids and alcohol. | [Air & Water Reactions]
Insoluble in water. Slowly hydrolyzed. | [Potential Exposure]
Dazomet is a dithiocarbamate insecti-
cide, herbicide, fumigant, fungicide, nematicide. It is used
as a soil fumigant used against germinating weed seeds,
soil insects, nematodes, and soil-borne diseases in forest
nursery seed beds, tobacco crops, greenhouse crops, and substrates for potted plants, turf, and ornamentals. It is also
used as an antimicrobial agent for slimicide preparations
and for adhesives, paper-mill slimicide, paint, and cooling
water slimicides. | [Fire Hazard]
Flash point data for this chemical are not available; however, DAZOMET is probably combustible. | [First aid]
If this chemical gets into the eyes, remove any
contact lenses at once and irrigate immediately for at least
15 minutes, occasionally lifting upper and lower lids. Seek
medical attention immediately. If this chemical contacts the
skin, remove contaminated clothing and wash immediately
with soap and water. Seek medical attention immediately.
If this chemical has been inhaled, remove from exposure,
begin rescue breathing (using universal precautions) if
breathing has stopped, and CPR if heart action has stopped.
Transfer promptly to a medical facility. When this chemical
has been swallowed, get medical attention. Give large
quantities of water and induce vomiting. Do not make an
unconscious person vomit. Do not induce vomiting when
formulations containing petroleum solvents are ingested. | [Shipping]
UN3077 Environmentally hazardous substances,
solid, n.o.s., Hazard class: 9; Labels: 9-Miscellaneous
hazardous material, Technical Name Required. | [Incompatibilities]
Sensitive to moisture and heat.
Decomposes on heating above 102
C, producing toxic
fumes including nitrogen oxides and sulfur oxides.
Dithiocarbamate esters are combustible. They react vio-
lently with powerful oxidizers such as calcium hypochlo-
rite. Poisonous gases are generated by the thermal
decomposition of Dithiocarbamate compounds, including
carbon disulfide, oxides of sulfur, oxides of nitrogen,
hydrogen sulfide, ammonia, and methylamine. Thio and
dithiocarbamates slowly decompose in aqueous solution to
form carbon disulfide and methylamine or other amines.
Such decompositions are accelerated by acids. Flammable
gases are generated by the combination of dithiocarbamate
with aldehydes, nitrides, and hydrides. Dithiocarbamate are
incompatible with acids, peroxides, and acid halides. | [Description]
Dazomet is a biocide used to control bacterial and
fungal growth in pulp and paper systems, but also in
agriculture for soil disinfection. It is contained in Busan
1058, Mylone and Fungicide 974 (Crag). Sensitization,
rarely reported, occurred in a paper-mill worker.
| [Chemical Properties]
White crystalline solid. Nearly odorless. | [Waste Disposal]
Do not discharge into drains
or sewers. Dispose of waste material as hazardous waste
using a licensed disposal contractor to an approved landfill.
Consult with environmental regulatory agencies for guid-
ance on acceptable disposal practices. Generators of waste
containing this contaminant (≥100 kg/mo) must conform
with EPA regulations governing storage, transportation,
treatment, and waste disposal. A potential candidate for
liquid injection incineration at a temperature range of
650℃
to 1600℃
and a residence time 0.1 to 2 seconds.
Also, a potential candidate for rotary kiln incineration at a
temperature range of 820℃
to 1600℃
and residence times
of seconds for liquids and gases, and hours for solids
.In
accordance with 40CFR165, follow recommendations for
the disposal of pesticides and pesticide containers.
Containers must be disposed of properly by following
package label directions or by contacting your local or
federal environmental control agency, or by contacting your
regional EPA office. | [Environmental Fate]
Soil. Soil metabolites include formaldehyde, hydrogen sulfide, methylamine and
methyl(methylaminomethyl)dithiocarbamic acid (Hartley and Kidd, 1987) which further
decomposes to methyl isothiocyanate (Harley and Kidd, 1987; Ashton and Monaco, 1991;
Cremlyn, 1991). The rate of decomposition is dependent upon the soil type, temperature
and humidity (Cremlyn, 1991).
Chemical/Physical. Hydrolyzes in acidic solutions forming carbon disulfide, methylamine and formaldehyde (Hartley and Kidd, 1987; Humburg et al., 1989). These compounds are probably formed following the decomposition of dazomet with alcohol and | [Metabolic pathway]
Dazomet is a propesticide that decomposes to generate the highly volatile
methyl isothiocyanate. The pathways of metabolism of methyl isothiocyanate
are described under its own entry. In soil, dazomet degrades mainly
via a dithiocarbamic acid which in turn affords methyl isothiocyanate,
formaldehyde, hydrogen sulfide and methy lamine. | [Degradation]
Dazomet is rapidly hydrolysed in acidic media to carbon disulfide, formaldehyde
and methylamine (PM). DT50 values for hydrolysis were 85,
490 and 110 hours at pH 5,7 and 9, respectively. It is sensitive to oxygen
and to light. |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,N | [Risk Statements ]
R22:Harmful if swallowed.
R36:Irritating to the eyes.
R50/53:Very Toxic to aquatic organisms, may cause long-term adverse effects in the aquatic environment . | [Safety Statements ]
S15:Keep away from heat .
S22:Do not breathe dust .
S24:Avoid contact with skin .
S60:This material and/or its container must be disposed of as hazardous waste .
S61:Avoid release to the environment. Refer to special instructions safety data sheet . | [RIDADR ]
UN3077 9/PG 3 | [WGK Germany ]
3 | [RTECS ]
XI2800000 | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29349990 | [Safety Profile]
Poison bj 7 in ' g estion and
intraperitoneal routes. Moderately toxic by
skin contact and subcutaneous routes. A
severe eye irritant. A mild primary skin
irritant and sensitizer. When heated to
decomposition it emits very toxic fumes of
NOx and SOx | [Hazardous Substances Data]
533-74-4(Hazardous Substances Data) | [Toxicity]
LD50 in rats, mice, guinea pigs, rabbits (g/kg): 0.32-0.62, 0.18, 0.16, 0.12 orally; in rats, rabbits, dogs (g/kg): 0.087, 0.127, 0.047-0.063 i.p.; in rabbits (g/kg): 7.1 dermally (Smyth) |
|
|