| Identification | More | [Name]
1-Bromo-2-(2-methoxyethoxy)ethane | [CAS]
54149-17-6 | [Synonyms]
1-BROMO-2-(2-METHOXYETHOXY)ETHANE
MONO METHOXY PEG BROMIDE
Ethane, 1-(2-bromoethoxy)-2-methoxy-
1-bromo-3,6-dioxaheptane
2-(2-Methoxyethoxy)ethyl bromide
1-BROMO-2-(2-METHOXYETHOXY)ETHANE, TECH. 90%, STAB. WITH SOD
1-BROMO-(2-METHOXYETHOXY)ETHANE
1-Bromo-2-(2-methoxyethoxy)ethane, tech. 90%, stab. with sodium carbonate
1-Bromo-2-(2-methoxyethoxy)ethane, tech. 90%
1-BROMO-2-(2-METHOXYETHOXY)ETHANE, 90%, STABILIZED WITH SODIUM CARBONATE
1-Bromo-2-(2-methoxyethoxy)ethane, stabilized with sodium carbonate
1-(2-Bromoethoxy)-2-methoxyethane
2-Bromoethyl 2-methoxyethyl ether | [EINECS(EC#)]
259-000-6 | [Molecular Formula]
C5H11BrO2 | [MDL Number]
MFCD00000238 | [Molecular Weight]
183.04 | [MOL File]
54149-17-6.mol |
| Chemical Properties | Back Directory | [Appearance]
CLEAR COLOURLESS LIQUID | [Boiling point ]
156 °C (lit.)
37-40 °C/0.01 mmHg (lit.) | [density ]
1.3600 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.455(lit.)
| [Fp ]
163 °F
| [storage temp. ]
Refrigerator (+4°C) | [form ]
Liquid | [color ]
Clear colorless to pale yellow | [Water Solubility ]
Not miscible in water. | [Sensitive ]
Light Sensitive | [BRN ]
2069579 | [InChI]
InChI=1S/C5H11BrO2/c1-7-4-5-8-3-2-6/h2-5H2,1H3 | [InChIKey]
HUXJXNSHCKHFIL-UHFFFAOYSA-N | [SMILES]
C(OCCBr)COC | [CAS DataBase Reference]
54149-17-6(CAS DataBase Reference) | [NIST Chemistry Reference]
1-Bromo-2-(2-methoxyethoxy)ethane(54149-17-6) |
| Safety Data | Back Directory | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [HS Code ]
29091990 |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless to pale yellow liquid | [Uses]
1-Bromo-2-(2-methoxyethoxy)ethane is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff. | [Synthesis]
General Procedure for Preparation of 1-Bromo-2-(2-methoxyethoxy)ethane: Into a 25-mL round bottomed flask equipped with magnetic stir bar, addition funnel and positive flow of nitrogen were placed 15.60 mmol of a ethyleneglycol monomethyl ether. The solution was stirred for 15 min in an ice bath before the dropwise addition of phosphorous tribromide (7.81 mmol) over a 10 min period. The solution was allowed to gradually warm and stir at room temperature (rt) for 14 hrs. The solution was then heated in a 90 °C oil bath for 1 hr, at which time the solution turned yellow. The solution was allowed to cool to rt, poured onto 30 g of ice/water mixture, and made slightly basic with addition of a 10% solution of NaHCO3 (~6 mL). Subsequent extraction with diethyl ether (Et2O) (3 x 30 mL), followed by drying over MgSO4 and concentration under reduced pressure afforded a colorless oil in sufficient purity for use in subsequent reactions.
|
|
|