ChemicalBook--->CAS DataBase List--->215181-61-6

215181-61-6

215181-61-6 Structure

215181-61-6 Structure
IdentificationBack Directory
[Name]

m-PEG2-Azide
[CAS]

215181-61-6
[Synonyms]

mPEG2-N3
azido-mPEG2
m-PEG2-Azide
1-Azido-2-(2-methoxyethoxy)ethane
1-(2-Azidoethoxy)-2-methoxyethane
1-(1-ethoxy-2-azido)-2-methoxyethane
m-PEG2-Azide,m-PEG2-N3,1-(2-Azidoethoxy)-2-methoxyethane
[Molecular Formula]

C5H11N3O2
[MDL Number]

MFCD19672689
[MOL File]

215181-61-6.mol
[Molecular Weight]

145.16
Chemical PropertiesBack Directory
[storage temp. ]

2-8°C
[solubility ]

Chloroform (Sparingly), Acetone (Slightly)
[form ]

Oil
[color ]

Pale Yellow to Light Yellow
[InChI]

1S/C5H11N3O2/c1-3-10-4-5(9-2)7-8-6/h5H,3-4H2,1-2H3
[InChIKey]

PHMWJDNVPGHYAD-UHFFFAOYSA-N
[SMILES]

[N+](=[N-])=NC(OC)COCC
Safety DataBack Directory
[Symbol(GHS) ]

Flame (GHS02)
GHS02
[Signal word ]

Danger
[Hazard statements ]

H226-H242
[Precautionary statements ]

P210-P233-P234-P240-P370+P378-P403+P235
[WGK Germany ]

WGK 3
[Storage Class]

5.2 - Organic peroxides and self-reacting hazardous materials
[Hazard Classifications]

Flam. Liq. 3
Self-react. C
Hazard InformationBack Directory
[Description]

m-PEG2-azide is a PEG linker containing reactive azide group. The azide group is reactive with alkyne, BCN, DBCO via Click Chemistry to yield a stable triazole linkage.
[Uses]

m-PEG2-azide is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG2-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
[References]

[1] Lepage ML, et al. Design, synthesis and photochemical properties of the first examples of iminosugar clustersbased on fluorescent cores. Beilstein J Org Chem. 2015 May 6;11:659-67. DOI:10.3762/bjoc.11.74
Spectrum DetailBack Directory
[Spectrum Detail]

m-PEG2-Azide(215181-61-6)1HNMR
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