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544707-20-2

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544707-20-2 Structure

544707-20-2 Structure
IdentificationBack Directory
[Name]

JNJ 10181457 dihydrochloride
[CAS]

544707-20-2
[Synonyms]

JNJ-10181457 (hydrochloride)
4-[3-[4-[Piperidinyl]but-1-ynyl]benzyl]morpholine dihydrochloride
[Molecular Formula]

C20H29ClN2O
[MOL File]

544707-20-2.mol
[Molecular Weight]

348.92
Chemical PropertiesBack Directory
[storage temp. ]

Store at -20°C
[solubility ]

Soluble to 100 mM in water and to 25 mM in ethanol
[form ]

Powder
Hazard InformationBack Directory
[Uses]

JNJ 10181457 Dihydrochloride is an inhibitor of the histamine H3 receptor.
[in vivo]

JNJ-10181457 (10 mg/kg, i.p., 60 min) reverses Imetit (HY-101173, 3 mg/kg, s.c.)-induced water licking in rats and Scopolamine (HY-N0296, 0.06 mg/kg, i.p.)-induced increasing of incorrect responding in DNMTP task[1].

[IC 50]

H3 Receptor
544707-20-2 suppliers list
Company Name: Shanghai EFE Biological Technology Co., Ltd.  
Telephone: 021-65675885 18964387627
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Company Name: Shanghai Hongye Biotechnology Co. Ltd  
Telephone: 400-9205774 400-920-5774
Website: www.glpbio.cn
Company Name: ChemeGen(Shanghai) Biotechnology Co.,Ltd.  
Telephone: 18818260767
Website: http://www.chemegen.com
Company Name: TargetMol Chemicals Inc.  
Telephone: 4008200310 15002144251
Website: https://www.targetmol.cn/
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