| Identification | Back Directory | [Name]
JNJ 10181457 dihydrochloride | [CAS]
544707-20-2 | [Synonyms]
JNJ-10181457 (hydrochloride)
4-[3-[4-[Piperidinyl]but-1-ynyl]benzyl]morpholine dihydrochloride | [Molecular Formula]
C20H29ClN2O | [MOL File]
544707-20-2.mol | [Molecular Weight]
348.92 |
| Hazard Information | Back Directory | [Uses]
JNJ 10181457 Dihydrochloride is an inhibitor of the histamine H3 receptor. | [in vivo]
JNJ-10181457 (10 mg/kg, i.p., 60 min) reverses Imetit (HY-101173, 3 mg/kg, s.c.)-induced water licking in rats and Scopolamine (HY-N0296, 0.06 mg/kg, i.p.)-induced increasing of incorrect responding in DNMTP task[1].
| [IC 50]
H3 Receptor |
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