| Identification | More | [Name]
L-Epinephrine hydrochloride | [CAS]
55-31-2 | [Synonyms]
(-)-3,4-dihydroxy-alpha-((methylamino)methyl)benzyl alcohol hydrochloride
adrenalin chloride
ADRENALINE CHLORIDE
l-epinephrine hydrochloride
(r)-4-(1-hydroxy-2-(methylamino)ethyl)-1,2-benzenediol hydrochloride
(-)-adrenalinehydrochlorid
3,4-dihydroxy-alpha-((methylamino)methyl)-,hydrochloride,(-)-benzylalcoho
4-(1-hydroxy-2-(methylamino)ethyl)-,hydrochloride,(r)-2-benzenediol
epinephrinechloride
gelatin-epinephrine
l-1-(3,4-dihydroxyphenyl)-2-methylamino-1-ethanolhydrochloride
l-adrenalinechloride
l-adrenalinehydrochloride
l-epinephrinechloride
l-methylaminoethanolcathecholhydrochloride
nci-c55663
supranephrinsolution
(R)-4-[1-hydroxy-2-(methylamino)ethyl]pyrocatechol hydrochloride
Epinephrine Hydrochloric Acid
EPINEPHRINE HYDROCHLORIC ACID, USP25 98.0+% | [EINECS(EC#)]
200-230-3 | [Molecular Formula]
C9H14ClNO3 | [MDL Number]
MFCD00801067 | [Molecular Weight]
219.67 | [MOL File]
55-31-2.mol |
| Questions And Answer | Back Directory | [Uses]
It stimulates β-receptors in the myocardium, conduction system, and sinoatrial node, increasing myocardial contractility, cardiac output, conduction speed, and heart rate. It activates β2-receptors in the skin, mucous membranes, and visceral blood vessels, particularly causing significant constriction of the renal arteries, while dilating skeletal muscles and coronary arteries. It stimulates bronchial β2-receptors, causing bronchodilation. It acts on hepatic and adipose-derived β2-receptors, promoting glycogen and fat breakdown and increasing blood glucose levels. Epinephrine hydrochloride can be used for the resuscitation of cardiac arrest and anaphylactic shock, and can also be used to treat other allergic diseases (such as bronchial asthma and urticaria). When used in combination with local anesthetics, it is beneficial for local hemostasis and prolonging the drug's effect. |
| Hazard Information | Back Directory | [General Description]
Crystals. Used medically as a cardiostimulant. | [Reactivity Profile]
EPINEPHRINE HYDROCHLORIDE(55-31-2) is readily destroyed by alkalis and oxidizing agents . | [Air & Water Reactions]
Water soluble [Merck]. | [Health Hazard]
SYMPTOMS: Adverse reactions include restlessness; anxiety; headache; tremor; weakness; dizziness; pallor; respiratory difficulties; palpitation; nausea and vomiting. | [Fire Hazard]
Flash point data for this chemical are not available, but EPINEPHRINE HYDROCHLORIDE is probably combustible. | [Mechanism of action]
By stimulating vascular alpha-adrenergic receptors, epinephrine causes vasoconstriction, thereby increasing vascular resistance and blood pressure. When administered in the conjunctiva, Epinephrine Hydrochloride binds to alpha-adrenergic receptors in the iris sphincter muscle, resulting in vasoconstriction, a decrease in the production of aqueous humor, and a lowering of intraocular pressure. Through its beta1 receptor-stimulating actions, epinephrine increases the force and rate of myocardial contraction and relaxes bronchial smooth muscle, resulting in bronchodilation.
| [Pharmacology]
Epinephrine Hydrochloride is the hydrochloride salt of the naturally occurring sympathomimetic amine with vasoconstricting, intraocular pressure-reducing, and bronchodilating activities.
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