| Identification | More | [Name]
DL-Octopamine hydrochloride | [CAS]
770-05-8 | [Synonyms]
(+/-)-1-(4-HYDROXYPHENYL)-2-AMINOETHANOL HYDROCHLORIDE
1-[P-HYDROXYPHENYL]-2-AMINOETHANOL HCL
1-[P-HYDROXYPHENYL]-2-AMINOETHANOL HYDROCHLORIDE
ALPHA-(AMINOMETHYL)-4-HYDROXYBENZENEMETHANOL HYDROCHLORIDE
DL-1-(4-HYDROXYPHENYL)-2-AMINOETHANOL HYDROCHLORIDE
DL-A-(AMINOMETHYL)-P-HYDROXYBENZYL ALCOHOL HYDROCHLORIDE
dl-alpha-(aminomethyl)-4-hydroxybenzyl alcohol hydrochloride
DL-OCTOPAMINE HYDROCHLORIDE
OCTAPAMINE HCL
OCTOPAMINE HCL
(+/-)-OCTOPAMINE HYDROCHLORIDE
OCTOPAMINE HYDROCHLORIDE
P-(+/-)-ALPHA-(AMINOMETHYL)HYDROXYBENZYL ALCOHOL, HCL
P-HYDROXYPHENYLAMINOETHANOL HYDROCHLORIDE
dl-octopamine
DL-alpha-(aminomethyl)-p-hydroxybenzylic alcohol hydrochloride
Octopamine(Norsynephrine)
DL-Octapamine hydrochloride.
OCTOPAMINE HCL(P)
OCTOPAMINE HCL(RG) | [EINECS(EC#)]
212-216-4 | [Molecular Formula]
C8H12ClNO2 | [MDL Number]
MFCD00012881 | [Molecular Weight]
189.64 | [MOL File]
770-05-8.mol |
| Chemical Properties | Back Directory | [Appearance]
solid | [Melting point ]
~170 °C (dec.)(lit.)
| [Boiling point ]
290℃[at 101 325 Pa] | [density ]
1.39[at 20℃] | [vapor pressure ]
0.002Pa at 20℃ | [storage temp. ]
2-8°C | [solubility ]
H2O: soluble
| [form ]
solid
| [color ]
white or off-white
| [Stability:]
Stable. | [Water Solubility ]
soluble | [Merck ]
13,6791 | [BRN ]
3915414 | [Major Application]
cleaning products
cosmetics
flavors and fragrances
food and beverages
personal care | [InChI]
InChI=1S/C8H11NO2.ClH/c9-5-8(11)6-1-3-7(10)4-2-6;/h1-4,8,10-11H,5,9H2;1H | [InChIKey]
PUMZXCBVHLCWQG-UHFFFAOYSA-N | [SMILES]
C(C1C=CC(=CC=1)O)(O)CN.Cl | [LogP]
-2.6 at 20.1℃ | [CAS DataBase Reference]
770-05-8(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S36:Wear suitable protective clothing .
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
3249 | [WGK Germany ]
3
| [REACH Registrations]
Active | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Aquatic Chronic 3
Eye Irrit. 2 |
| Hazard Information | Back Directory | [Chemical Properties]
solid | [Originator]
Norfen,Morishita, Japan ,1975 | [Uses]
A biogenic amine that is the phenol analog of Noradrenaline. It is a neurosecretory product found in several vertebrates and invertebrates. Adrenergic. | [Uses]
Hypertensive;Adrenergic receptor agonist | [Manufacturing Process]
A solution of 33 grams of anhydrous aluminum chloride in 60 grams of nitrobenzene, to which a mixture of 14 grams of phenol and 9.3 grams of hydrochloride of amino-acetonitrile was added, had dry hydrochloric acid gas introduced into it for 3 hours, while stirring and cooling to keep the temperature between 20° and 30°C. The reaction mixture was then poured, with cooling, into 70 cc of water and the deposit obtained was sucked off, washed with acetone and dissolved in 300 cc of water. The solution thus prepared was decolorized with carbon, 50 grams of 30% sodium citrate solution was added to it, and then it was made slightly alkaline with ammonia. Thereupon hydroxy-4'-phenyl-1-amino-2-ethanone crystallized out in the form of leaflets. The yield was 7.7 grams.
The hydrochloride of this base, obtained by evaporation to dryness of a solution of the base in dilute hydrochloric acid and subsequent treatment of the residue with ethyl alcohol and acetone, had a chlorine content of 18.84%, (calculated, 18.90%).
This hydrochloride, on being dissolved in water and hydrogenated with hydrogen and a nickel catalyst, gave a good yield of hydrochloride of hydroxy4'-phenyl-1-amino-2-ethanol melting, after crystallization from a mixture of ethyl alcohol and butanone-2, at from 177° to 179°C with decomposition
| [Therapeutic Function]
Hypertensive | [General Description]
Octopamine is a biogenic amine, which functions as a neurotransmitter, neuromodulator and neurohormone. It is used to regulate various behaviors, such as learning, memory and aggression. Octopamine is present in mammalian tissues, human urine and invertebrates. | [Flammability and Explosibility]
Notclassified | [Biological Activity]
Invertebrate biogenic amine neurotransmitter, related to noradrenalin, that is an adrenoceptor agonist. Stimulates lipolysis in mammalian adipocytes via activation of β 3 receptors. Has dual effect on glucose transport in adipocytes: inhibits transport via β 3 receptor activation but stimulates transport when oxidised by MAO. Also activates human α 2A receptors, inhibiting subsequent cAMP production. | [Mode of action]
Octopamine hydrochloride is an invertebrate biogenic amine neurotransmitter, related to noradrenalin, that is an adrenoceptor (AR) agonist. Octopamine hydrochloride stimulates lipolysis in mammalian adipocytes via activation of β3-AR receptors. Has dual effect on glucose transport in adipocytes: inhibits transport via β3-AR receptor activation but stimulates transport when oxidised by MAO. Also activates human α2A-AR receptors, inhibiting subsequent cAMP production. |
|
| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
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| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
| Company Name: |
Maya High Purity Chemicals
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| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
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www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
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