| Identification | More | [Name]
Tanshinone I | [CAS]
568-73-0 | [Synonyms]
1,6,6-TRIMETHYL-6,7,8,9-TETRAHYDRO-PHENANTHRO[1,2-B]FURAN-10,11-DIONE
1,6-dimethyl-phenanthro[1,2-b]furan-10,11-dione
3,8,8-TRIMETHYL-8,9,10,11-TETRAHYDROPHENANTHRO[1,2-B]FURAN-1,2-DIONE
AKOS NCG1-0066
TANSHINONE I
TANSHINONE IIA
TANSHINONES IIA
TANSHINON I
Tanshinone
TANSHINONE I >98% BY HPLC FROM SALVIA MILTIORRHIZA B.
Phenanthro[1,2-b]furan-10,11-dione,1,6-dimethyl-
TanshinoneⅠ | [Molecular Formula]
C19H18O3 | [MDL Number]
MFCD00238692 | [Molecular Weight]
294.34 | [MOL File]
568-73-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
233-234°C | [Boiling point ]
498.0±24.0 °C(Predicted) | [density ]
1.324±0.06 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [solubility ]
DMSO: soluble1mg/mL | [form ]
powder | [color ]
red | [Major Application]
metabolomics
vitamins, nutraceuticals, and natural products | [InChI]
InChI=1S/C18H12O3/c1-9-4-3-5-12-11(9)6-7-13-15(12)17(20)16(19)14-10(2)8-21-18(13)14/h3-8H,1-2H3 | [InChIKey]
AIGAZQPHXLWMOJ-UHFFFAOYSA-N | [SMILES]
O1C=C(C)C2C(=O)C(=O)C3=C(C1=2)C=CC1=C3C=CC=C1C | [LogP]
4.312 (est) | [CAS DataBase Reference]
568-73-0(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
Purple to Brown powder | [Uses]
Tanshinone I is an extract from Danshen (Radix Salvia miltiorrhizae) and has been used for the treatment of cerebrovascular diseases such as ischemic stroke. | [Definition]
ChEBI: Tanshinone I is an abietane diterpenoid. It has a role as an anticoronaviral agent. | [Biological Activity]
Phenanthrenequinone constituent of Chinese medicinal herb Danshen (Salvia miltiorrhiza). Modulates or prevents breast cancer metastasis by regulating adhesion molecules. Anti-inflammatory.''TanshinoneI is extensively studied for its anticancer propertiesit was reported to inhibit cancer cell invasionmetastasisand migration and is a potent antitumor agent. It also displays antibacterialneuroprotectivememory-enhancingand cardioprotective activities. | [Cytotoxicity]
IC50 (μg/mL): 2.96 (A549), 2.14 (TOV-21G) (Chang et al. 2013)
IC50 (μg/mL): 10.5 (MIAPaCa-2) (Fronzaet al. 2011) |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
China Langchem Inc.
|
| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
|