| Identification | Back Directory | [Name]
TanshinoneIIA | [CAS]
69659-80-9 | [Synonyms]
DS 201
Sodium 1,6,6-trimeth
Sodium Tanshinon Ⅱ Asilate
Sodium TanshinonⅡA SilateA
Sulfotanshinone sodiuM II-A
Tanshinone ⅡASulfonate SodiuM
Tanshinone ⅡA-sulfonic sodium
SodiuM tanshinone IIA sulfonate
Sulfotanshinone SodiuM Injection
Tanshinone IIA sulfonate (sodium)
Tanshinone IIA sodium sulfonate 69659-80-9
Tanshinone II-A sodium sulfonate (DS-201), Pubchem CID: 23669322
1,6,6-trimethyl-10,11-dioxo-8,9-dihydro-7H-naphtho[1,2-g][1]benzofuran-2-sulfonate
SODIUM;1,6,6-TRIMETHYL-10,11-DIOXO-8,9-DIHYDRO-7H-NAPHTHO[1,2-G][1]BENZOFURAN-2-SULFONATE
SodiuM 1,6,6-triMethyl-10,11-dioxo-6,7,8,9,10,11-hexahydrophenanthro[1,2-b]furan-2-sulfonate
Phenanthro[1,2-b]furan-2-sulfonicacid, 6,7,8,9,10,11-hexahydro-1,6,6-triMethyl-10,11-dioxo-, sodiuM salt (1:1) | [Molecular Formula]
C19H19NaO6S | [MDL Number]
MFCD09028094 | [MOL File]
69659-80-9.mol | [Molecular Weight]
398.4 |
| Chemical Properties | Back Directory | [Melting point ]
To dark to Visualize | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Solid | [color ]
Red | [Water Solubility ]
H2O: 2mg/mL, clear (warmed) | [InChI]
InChI=1S/C19H18O6S.Na.H/c1-9-13-15(20)16(21)14-10-5-4-8-19(2,3)12(10)7-6-11(14)17(13)25-18(9)26(22,23)24;;/h6-7H,4-5,8H2,1-3H3,(H,22,23,24);; | [InChIKey]
HJOROJKIZHZOCZ-UHFFFAOYSA-N | [SMILES]
CC1=C(OC2C3C=CC4C(CCCC=4C=3C(=O)C(=O)C1=2)(C)C)S(O)(=O)=O.[NaH] |
| Hazard Information | Back Directory | [Chemical Properties]
Red crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from the rhizome of Salvia miltiorrhiza. | [Uses]
Sodium 1,6,6-Trimethyl-10,11-dioxo-6,7,8,9,10,11-hexahydrophenanthro[1,2-b]furan-2-sulfonate is an anti-oxidant for ameliorating hemorrhagic shock (HS)-induced organ failure or function. Asthma treatment. | [Biological Activity]
Tanshinone II A sulfonate is a water-soluble derivative of tanshinone II A th at exhibits anti-inflammatory properties in rodent models of hepatitis and sepsis. Tanshinone II A sulfonate targets Ca2+-activated potassium channels and carboxylesterase 2. Recent studies indicate th at tanshinone II A sulfonate but not tanshinone II A acts as potent negative allosteric modulator of the human purinergic receptor P2X7. |
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