| Identification | More | [Name]
2-Bromo-5-fluorobenzonitrile | [CAS]
57381-39-2 | [Synonyms]
2-BROMO-5-FLUOROBENZONITRILE
Bromofluorobenzonitrile2
2-Bromo-5-fluorobenzonitrile 99%
2-Bromo-5-fluorobenzonitrile99%
2-Bromo-5-fluorobenzonitrile, 98+% | [EINECS(EC#)]
260-711-9 | [Molecular Formula]
C7H3BrFN | [MDL Number]
MFCD00142875 | [Molecular Weight]
200.01 | [MOL File]
57381-39-2.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,T,Xi | [Risk Statements ]
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [RIDADR ]
3439 | [WGK Germany ]
3
| [Hazard Note ]
Toxic | [HazardClass ]
6.1 | [PackingGroup ]
III | [HS Code ]
29269090 |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless solid | [Uses]
2-Bromo-5-fluorobenzonitrile may be used in the preparation of 5-chloro-4,2?-difluorobiphenyl-2-carbonitrile. | [Uses]
2-Bromo-5-fluorobenzonitrile is used in the synthesis of pyrimidine functional compounds acting as GABAAα2/α3 binding site agonists used in the treatment of anxiety disorders. | [General Description]
2-Bromo-5-fluorobenzonitrile can be prepared from 3-fluorobenzonitrile vial bromination using 1,3-dibromo-5,5-dimethylhydantoin (DBDMH).. It undergoes palladium-catalyzed Suzuki coupling with boronic acid derivative to form corresponding biaryl. |
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