| Identification | Back Directory | [Name]
HEPARIN MONOSULFATE SODIUM SALT | [CAS]
57459-72-0 | [Synonyms]
Leparan
suleparoid
Aids031652
Aids-031652
HeparanSulphate
suleparoid sodium
HEPARITIN SULFATE
heparin monosulfate
Sodium heparan sulfate
Sodium heparitin sulfate
HEPARIN SULFATE SODIUM SALT
HEPARAN SULFATE SODIUM SALT
Heparan sulphate sodium salt
HEPARAN SULFATE I SODIUM SALT
HEPARITIN SULFATE SODIUM SALT
HEPARIN MONOSULFATE SODIUM SALT
HEPARIN SULFATE BOVINE SODIUM SALT
HEPARAN SULFATE, SODIUM SALT, BOVINE
HEPARIN MONOSULFATE BOVINE SODIUM SALT
HEPARITIN SULFATE SODIUM-POTASSIUM SALT
HEPARIN MONOSULFATE SODIUM-POTASSIUM SALT
heparan sulfate sodium from bovine*kidney
N-ACETYLHEPARAN SULFATE BOVINE SODIUM SALT
HEPARAN SULFATE SODIUM SALT FROM BOVINE KIDNEY
HEPARIN SULFATE = HEPARAN SULFATE I SODIUM SALT
heparan sulfate fast-moving fraction:*sodium bovi
HEPARAN SULFATE FAST-MOVING FRACTION,*SO DIUM, PORCI
heparan sulfate fast-moving fraction sodium salt from porcine intestinal mucosa | [EINECS(EC#)]
232-939-9 | [MDL Number]
MFCD00131294 |
| Hazard Information | Back Directory | [Chemical Properties]
Also available fractionated heparan sulfates with lower molecular weights and different Anti-IIa activities. | [Uses]
Antithrombotic. | [Uses]
Heparan sulfate sodium salt from bovine kidney has been used:
- to investigate its effect on proliferation of B cells
- to monitor its role on eye development in E5 embryonic cells
- to study its binding with exosome fibronectin in human trabecular meshwork cells using dot blot
| [Brand name]
Orgaran (Organon). | [Biochem/physiol Actions]
Heparan sulphate (HS), a ubiquitous glycosaminoglycan, is a polymer of D-glucuronic acid or L-iduronic acid and D-glucosamine (GlcA) sugars. It is synthesized in the cis-Golgi as heparan. In Golgi, final heparan sulphate is synthesized in by the action of enzymes N- and O-HS-sulphotransferases and HS epimerase. The mature HS has 50 to 200 disaccharide units. It is part of the extracellular matrix (ECM) and plays a key role in the oncogenic pathway. Deregulation of heparin sulfate metabolism is implicated in cancer progression. HS is associated with the onset of infectious diseases and inflammatory conditions. HS interaction with Aβ fibrils contributes to the pathophysiology of Alzheimer′s disease. |
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| Company Name: |
Sigma-Aldrich
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| Telephone: |
021-61415566 800-8193336 |
| Website: |
https://www.sigmaaldrich.cn |
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