ChemicalBook--->CAS DataBase List--->9045-22-1

9045-22-1

9045-22-1 Structure

9045-22-1 Structure
IdentificationBack Directory
[Name]

HEPARIN LITHIUM SALT
[CAS]

9045-22-1
[Synonyms]

LithiuM heparin
HEPARIN LITHIUM
HEP, LI, PORCINE
Heparin,lithiumsal
Erucic Acid 112-86-7
HEPARIN LITHIUM SALT
PORCINE HEPARIN, LITHIUM
Heparin, LithiuM salt USP
HEPARIN PORCINE LITHIUM SALT
HEPARIN, LITHIUM SALT, PORCINE
HEPARIN LITHIUM SALT USP/EP/BP
Heparin lithium salt, ~200 units/mg
Heparin lithium salt [>170 units/mg]
Heparin lithium salt/ Heparin lithium
Heparin lithium salt, ≥150 USP units/mg
Heparin lithiuM salt ,0% [>170 units/Mg]
heparin lithium from porcine*intestinal mucosa
Heparin, Lithium Salt, PorcineIntestinal Mucosa
HEPARIN LITHIUM SALT FROM HOG INTESTINE ~190 U/MG
Heparin lithium salt from porcine intestinal mucosa
Heparin lithium salt, 170 units/mg, from porcine intestinal mucosa
Heparin, Lithium Salt, Porcine Intestinal Mucosa - CAS 9045-22-1 - Calbiochem
[EINECS(EC#)]

686-293-1
[Molecular Formula]

n.a.
[MDL Number]

MFCD00131308
Chemical PropertiesBack Directory
[storage temp. ]

+15C to +30C
[form ]

White solid
[color ]

White to off-white
[Water Solubility ]

Water: 125 mg/mL
[EPA Substance Registry System]

Heparin, lithium salt (9045-22-1)
Safety DataBack Directory
[Hazard Codes ]

Xi
[Risk Statements ]

36/37/38
[Safety Statements ]

22-24/25-36-26
[WGK Germany ]

3
[RTECS ]

MI0700000
[F ]

3-10
[TSCA ]

TSCA listed
[HS Code ]

29319090
Hazard InformationBack Directory
[Chemical Properties]

White powder
[Uses]

diuretic
[Biological Activity]

Heparin Lithium salt is an anticoagulant that binds reversibly to antithrombin III (ATIII). Heparin Lithium salt is used as an anticoagulant for laboratory studies and in direct membrane-feeding assays.
[Synthesis]

1) Enzymatic digestion of crude heparin: dissolve the crude heparin sodium, adjust the PH value of 7.5-9.0, warm up to 50-55℃, add heparin enzyme trypsin, keep warm for 4-5 hours, adjust the PH value of 9.0-11. After warming to 85°C t

[storage]

4°C, protect from light
[References]

[1] Purushothaman, Anurag, et al. "Fibronectin on the surface of myeloma cell-derived exosomes mediates exosome-cell interactions." Journal of Biological Chemistry 291.4 (2016): 1652-1663. DOI:10.1074/jbc.M115.686295.
[2] Capila, Ishan, and Robert J. Linhardt. "Heparin–protein interactions." Angewandte Chemie International Edition 41.3 (2002): 390-412.
[3] Bj?rk, I., and U. Lindahl. "Mechanism of the anticoagulant action of heparin." Molecular and cellular biochemistry 48 (1982): 161-182. DOI:10.1007/BF00421226.
[4] Le Brigand, H., et al. "Prevention of postoperative thrombo-embolic accidents following thoracic surgery by low-dose calcium heparinate: a comparative study (author's transl)." La Semaine des Hopitaux: Organe Fonde par L'association D'enseignement Medical des Hopitaux de Paris 57.19-20 (1981): 972-977.
[5] Beeler, D., R. Rosenberg, and R. Jordan. "Fractionation of low molecular weight heparin species and their interaction with antithrombin." Journal of Biological Chemistry 254.8 (1979): 2902-2913.
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