| Identification | Back Directory | [Name]
Ethanol, 2-[2-(2-bromoethoxy)ethoxy]- | [CAS]
57641-67-5 | [Synonyms]
Bromo-PEG3
Br-PEG3-OH
57641-67-5
CAS_57641-67-5
2-(2-(2-bromoethoxy)ethoxy)ethanol
Ethanol, 2-[2-(2-bromoethoxy)ethoxy]-
2-(2-(2-Bromoethoxy)ethoxy)ethan-1-ol | [Molecular Formula]
C6H13BrO3 | [MDL Number]
MFCD18205854 | [MOL File]
57641-67-5.mol | [Molecular Weight]
213.07 |
| Chemical Properties | Back Directory | [Boiling point ]
276.3±20.0 °C(Predicted) | [density ]
1.411±0.06 g/cm3(Predicted) | [storage temp. ]
Sealed in dry,Room Temperature | [solubility ]
Soluble in Water, DMSO, DMF, DCM | [form ]
Liquid | [pka]
14.36±0.10(Predicted) | [color ]
Light yellow to yellow | [InChI]
InChI=1S/C6H13BrO3/c7-1-3-9-5-6-10-4-2-8/h8H,1-6H2 | [InChIKey]
JYRDRGOLCZHQJZ-UHFFFAOYSA-N | [SMILES]
C(O)COCCOCCBr |
| Hazard Information | Back Directory | [Description]
Bromo-PEG3-alcohol is a PEG linker containing a bromide group with a terminal hydroxyl group. The hydrophilic PEG spacer increases solubility in aqueous media. The bromide (Br) is a very good leaving group for nucleophilic substitution reactions. The hydroxyl group enables further derivatization or replacement with other reactive functional groups. | [Uses]
Br-PEG3-OH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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| Company Name: |
parabiochem
|
| Telephone: |
025-83453382-8005 |
| Website: |
www.parabiochem.cn |
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