| Identification | More | [Name]
2-Bromomethyl-1,3-dioxolane | [CAS]
4360-63-8 | [Synonyms]
2-BROMOMETHYL-1,3-DIOXOLANE
BROMOACETALDEHYDE ETHYLENE ACETAL
1,3-Dioxolane, 2-(bromomethyl)-
2-(bromomethyl)-3-dioxolane
2-(BROMOMETHYL)-1,3-DIOXOLANE/BROMOACETALDEHYDE ETHYLENE ACETAL
2-Bromomethyl-1,3-dioxolane, 97 % | [EINECS(EC#)]
224-443-6 | [Molecular Formula]
C4H7BrO2 | [MDL Number]
MFCD00003214 | [Molecular Weight]
167 | [MOL File]
4360-63-8.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless liquid | [Boiling point ]
80-82 °C27 mm Hg(lit.)
| [density ]
1.613 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.482(lit.)
| [Fp ]
145 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Chloroform, Ethyl Acetate (Slightly) | [form ]
Liquid | [color ]
Clear colorless | [Water Solubility ]
Immiscible with water. | [Sensitive ]
Moisture Sensitive | [Detection Methods]
GC,NMR | [BRN ]
103309 | [InChIKey]
CKIIJIDEWWXQEA-UHFFFAOYSA-N | [CAS DataBase Reference]
4360-63-8(CAS DataBase Reference) | [NIST Chemistry Reference]
2-Bromomethyl-1,3-dioxolane(4360-63-8) | [Storage Precautions]
Moisture sensitive | [EPA Substance Registry System]
4360-63-8(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S24/25:Avoid contact with skin and eyes . | [WGK Germany ]
3
| [TSCA ]
Yes | [HS Code ]
29049090 |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless liquid | [Uses]
2-Bromomethyl-1,3-dioxolane is used in the preparation of alfa, beta-unsaturated aldehyde and 1, 4-two aldehyde monoacetals synthesis of monomers. | [Synthesis]
10.326 kg (166.3 mol) of ethylene glycol and 3.66 kg (83.185 mol) of freshly distilled acetaldehyde were added to the reaction vessel with slow stirring at room temperature for 30 minutes. Slowly 14.622 kg (91.504 mol) of bromine was added dropwise, with the rate of dropwise acceleration being controlled to maintain the reaction temperature at 0-3 °C. After the dropwise addition was completed, the reaction was continued at 0-3 °C for 3.5 hours. Upon completion of the reaction, decompression distillation was carried out to collect the fraction at 80-82 °C/3.6 kPa to give 11.002 kg (65.883 mol) of 2-bromomethyl-1,3-dioxolane in 79.2% yield, which was analyzed to be greater than 95%. | [References]
[1] Patent: CN105418612, 2016, A. Location in patent: Paragraph 0028; 0039; 0040 |
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