| Identification | More | [Name]
2,2-Dimethylbutyryl chloride | [CAS]
5856-77-9 | [Synonyms]
2,2-dimethylbutanoyl chloride
2,2-DIMETHYLBUTYRYL CHLORIDE
2,2-Dimethylbutyricacidchloride
Dimethylbutyrylchloride
2,2-dimethylbutyl chloride | [EINECS(EC#)]
227-478-5 | [Molecular Formula]
C6H11ClO | [MDL Number]
MFCD03093071 | [Molecular Weight]
134.6 | [MOL File]
5856-77-9.mol |
| Chemical Properties | Back Directory | [Melting point ]
-20 °C | [Boiling point ]
133°C | [density ]
0,98 g/cm3 | [refractive index ]
1.4240 | [Fp ]
29°C | [storage temp. ]
Hygroscopic, Refrigerator, under inert atmosphere | [solubility ]
Chloroform, Ethyl Acetate | [form ]
Oil | [color ]
Clear Colorless | [Water Solubility ]
Reacts with water. Soluble in chloroform and ethyl acetate. | [Sensitive ]
Moisture Sensitive | [BRN ]
1743935 | [InChI]
InChI=1S/C6H11ClO/c1-4-6(2,3)5(7)8/h4H2,1-3H3 | [InChIKey]
LDJUYMIFFNTKOI-UHFFFAOYSA-N | [SMILES]
C(Cl)(=O)C(C)(C)CC | [CAS DataBase Reference]
5856-77-9(CAS DataBase Reference) |
| Hazard Information | Back Directory | [Chemical Properties]
Colorless liquid | [Uses]
,2-Dimethylbutanoyl chloride is a reagent that is used in the synthesis of 4α,5-Dihydro Simvastatin, the drug, is sold under the trade name Zocor. A competitive inhibitor of HMG-CoA reductase. A synthetic analog of Lovastatin. Antilipemic. | [Application]
2,2-Dimethylbutyryl chloride has been shown to be a potent CB2 receptor agonist in vitro. It can also be used as an effective acid catalyst for various organic reactions.
| [Hazard]
2,2-Dimethylbutyryl chloride is a flammable liquid, it causes severe skin burns and eye damage.
| [Synthesis]
Under stirring, 25.6g of 2,2-dimethylbutyric acid and 35.8g of sulfoxide chloride were added to a three-necked flask, heated to reflux, and the hydrogen chloride and sulfur dioxide gases were absorbed with alkali. After no gas was produced, the excess sul |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
|
| Telephone: |
400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
|
| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
Jia Xing Isenchem Co.,Ltd
|
| Telephone: |
0573-85285100 18627885956 |
| Website: |
https://www.chemicalbook.com/ShowSupplierProductsList14265/0_EN.htm |
| Company Name: |
Maya High Purity Chemicals
|
| Telephone: |
+86 (573) 82222445 (0)18006601000 452520369 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15221/0_EN.htm |
|