| Identification | More | [Name]
3-Methoxyacetophenone | [CAS]
586-37-8 | [Synonyms]
1-(3-methoxyphenyl)ethanone
3-ACETANISOLE
3-ACETOANISOLE
3-ACETYLANISOLE
3'-METHOXYACETOPHENONE
3-METHOXYACETOPHENONE
AKOS BBS-00003224
M-ACETANISOLE
M-ACETYLANISOLE
M-METHOXYACETOPHENONE
1-Acetyl-3-methoxybenzene
Acetophenone, 3'-methoxy-
Acetophenone, m-methoxy-
Ethanone,1-(3-methoxyphenyl)-
meta-Methoxyacetophenone
Methyl 3-methoxyphenyl ketone
m-Methoxyacetophennone
3'-Methoxyacetophenone m-Acetanisole 3-Acetanisole
3-Methoxyacetophenone,>99%
3-Methoxyacetophenone,97% | [EINECS(EC#)]
209-573-3 | [Molecular Formula]
C9H10O2 | [MDL Number]
MFCD00008736 | [Molecular Weight]
150.17 | [MOL File]
586-37-8.mol |
| Chemical Properties | Back Directory | [Appearance]
clear slightly yellow to slightly brown liquid | [Melting point ]
-7 °C
| [Boiling point ]
239-241 °C(lit.)
| [density ]
1.094 g/mL at 25 °C(lit.)
| [vapor pressure ]
2.41-10.665Pa at 20-25℃ | [refractive index ]
n20/D 1.542(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
Chloroform (Slightly), Ethyl Acetate (Slightly) | [form ]
Liquid | [color ]
Clear slightly yellow to slightly brown | [Specific Gravity]
1.094 | [Water Solubility ]
Fully miscible in water. Soluble in alcohol. | [Sensitive ]
Light Sensitive | [BRN ]
878552 | [Henry's Law Constant]
1.9×101 mol/(m3Pa) at 25℃, Ji et al. (2008) | [InChI]
1S/C9H10O2/c1-7(10)8-4-3-5-9(6-8)11-2/h3-6H,1-2H3 | [InChIKey]
BAYUSCHCCGXLAY-UHFFFAOYSA-N | [SMILES]
COc1cccc(c1)C(C)=O | [LogP]
1.86-2.085 at 20-25℃ | [CAS DataBase Reference]
586-37-8(CAS DataBase Reference) | [NIST Chemistry Reference]
Ethanone, 1-(3-methoxyphenyl)-(586-37-8) |
| Questions And Answer | Back Directory | [Synthesis]
5,5'-Dimethyl-2,2'-Bipyridine 8 (4.10 mg, 0.023 mmol, 15 mol%), MgCl2 (28.4 mg, 0.300 mmol, 200 mol%), Ni(acac)2 (5.90 mg, 0.023 mmol, 15 mol%), and zinc powder (29.4 mg, 0.450 mmol, 300 mol%) were placed into a flame-dried Schlenk tube equipped with a magnetic stir bar. The tube was then transferred to a dry glove box, and TBAI (27.7 mg, 0.075 mmol, 50 mol%) was added. The tube was covered with a rubber diaphragm and then removed from the glove box. Then, acidic chloride (0.225 mmol, 150 mol%), methanesulfonate (0.150 mmol, 100 mol%), THF (0.8 mL), and CH3CN (0.2 mL) were added via syringe. The reaction mixture was stirred for 12 hours at 30°C under a N2 atmosphere and then directly loaded onto a silica gel column without further treatment. The reaction vessel was rinsed with a small amount of DCM to remove any residue. Rapid column chromatography (SiO2: ethyl acetate in hexane) was performed. 1-(3-methoxyphenyl)acetone (38). 21 was prepared using 3-methoxybenzoyl chloride (0.225 mmol, 150 mol%) and methanesulfonate (0.150 mmol, 100 mol%). After purification by column chromatography (SiO2: 10% ethyl acetate in hexane), a colorless oily 3-methoxyacetophenone (10.8 mg, 48% yield) was obtained. 
|
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H315-H319-H335 | [Precautionary statements ]
P271-P261-P280 | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R36/38:Irritating to eyes and skin .
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) .
S24/25:Avoid contact with skin and eyes .
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [Hazard Note ]
Irritant | [REACH Registrations]
Active | [HS Code ]
29145000 | [Storage Class]
10 - Combustible liquids | [Hazard Classifications]
Acute Tox. 4 Oral
Aquatic Chronic 3
Eye Irrit. 2
Skin Irrit. 2 |
| Hazard Information | Back Directory | [Chemical Properties]
clear slightly yellow to slightly brown liquid | [Uses]
It is applied in the asymmetric transfer hydrogenation of ketones catalyzed by ruthenium(II) complexes. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 109, p. 7137, 1987 DOI: 10.1021/ja00257a038
Synthesis, p. 406, 1987 DOI: 10.1055/s-1987-27965 | [Flammability and Explosibility]
Nonflammable |
|
| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
Alfa Aesar
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400-6106006 |
| Website: |
http://chemicals.thermofisher.cn |
| Company Name: |
Energy Chemical
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| Telephone: |
400-0056266 |
| Website: |
www.energy-chemical.com |
| Company Name: |
China Langchem Inc.
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| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
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