60696-83-5

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60696-83-5 Structure

Identification	Back Directory
[Name] m-PEG3-Ms
[CAS] 60696-83-5
[Synonyms] m-PEG2-Ms Methyl-PEG2-MS 2-(2-Methoxyethoxy)ethyl methanesulfonate methanesulfonicacid2-(2-methoxyethoxy)ethylester Ethanol, 2-(2-methoxyethoxy)-, 1-methanesulfonate
[Molecular Formula] C6H14O5S
[MDL Number] MFCD00955893
[MOL File] 60696-83-5.mol
[Molecular Weight] 198.24

Hazard Information	Back Directory
[Description] m-PEG3-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.
[Uses] m-PEG2-MS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50] PEGs
[References] [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005

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