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130955-37-2

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Identification

130955-37-2 Structure

Identification	Back Directory
[Name] m-PEG5-Ms
[CAS] 130955-37-2
[Synonyms] PEG4-Oms m-PEG5-Ms 2,5,8,11-Tetraoxatridecan-13-yl methanesulfonate 2,5,8,11-Tetraoxatridecan-13-ol, 13-methanesulfonate
[Molecular Formula] C10H22O7S
[MDL Number] MFCD30723269
[MOL File] 130955-37-2.mol
[Molecular Weight] 286.34

Chemical Properties	Back Directory
[storage temp. ] Storage temp. 2-8°C
[form ] Liquid
[color ] Colorless to light yellow

Hazard Information

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[Description]

m-PEG5-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases solubility in aqueous media.

[Uses]

m-PEG4-MS is a PEG-based PROTAC linker can be used in the synthesis of PROTACs. m-PEG4-MS is a cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Biological Activity]

m-PEG4-Ms is a PROTAC bridge and belongs to the PEG class. m-PEG4-Ms can be used to synthesize a series of PROTAC molecules. It is a cleavable ADC bridge for the synthesis of antibody drug conjugates (ADCs).

[target]

Cleavable

PEGs

[IC 50]

Cleavable Linker; PEGs

[References]

[1] Sanxing Sun, et al. Triazolotriazine derivatives as a2a receptor antagonists. WO2020002969A1.

Spectrum Detail	Back Directory
[Spectrum Detail] m-PEG5-Ms(130955-37-2)¹HNMR

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