| Chemical Properties | Back Directory | [Boiling point ]
660.4±55.0 °C(Predicted) | [density ]
1.137±0.06 g/cm3(Predicted) | [InChI]
InChI=1S/C26H54O15S/c1-29-3-4-30-5-6-31-7-8-32-9-10-33-11-12-34-13-14-35-15-16-36-17-18-37-19-20-38-21-22-39-23-24-40-25-26-41-42(2,27)28/h3-26H2,1-2H3 | [InChIKey]
JKPOVWOBYWMPRZ-UHFFFAOYSA-N | [SMILES]
C(OS(C)(=O)=O)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC |
| Hazard Information | Back Directory | [Description]
m-PEG13-Ms is a PEG linker containing a mesyl group. The mesyl group is a good leaving group for nucleophilic substitution reactions. The hydrophilic PEG spacer increases the water solubility of compounds in aqueous media. | [Uses]
Ms-PEG12-m is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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