ChemicalBook--->CAS DataBase List--->6157-87-5

6157-87-5

6157-87-5 Structure

6157-87-5 Structure
IdentificationBack Directory
[Name]

trestolone acetate
[CAS]

6157-87-5
[Synonyms]

U-15614
NSC-69948
Trestolone acetate (MENT)
IVCRCPJOLWECJU-XQVQQVTHSA-N
trestolone acetate USP/EP/BP
3-Oxo-7α-methylestra-4-ene-17β-ol acetate
17β-Hydroxy-7α-methylestr-4-en-3-one acetate
Trestolone Acetate (1.0mg/ml in Acetonitrile)
Acetic acid 3-oxo-7α-methylestra-4-ene-17β-yl ester
Estr-4-en-3-one, 17-(acetyloxy)-7-methyl-, (7α,17β)-
[EINECS(EC#)]

-0
[Molecular Formula]

C21H30O3
[MDL Number]

MFCD00271621
[MOL File]

6157-87-5.mol
[Molecular Weight]

330.465
Questions And AnswerBack Directory
[Synthesis]

trestolone acetate was prepared as follows:

Tetrahydrofuran (717.6 g), compound (5A) (204 g), and anhydrous copper acetate (II) (23.6 g) were placed in a suitable container. The slurry was stirred and cooled to between -45°C and -35°C. Then, methylmagnesium chloride solution (23%, dissolved in THF, analytical concentration 22.6%, 346.1 g) was slowly added at a rate that maintained the reaction temperature between -45°C and -35°C for a minimum of 3 hours. After the addition was complete, the reaction mixture was stirred between -45°C and -35°C and monitored by HPLC. Then, the mixture was finished with 37% hydrochloric acid (128.1 g), maintaining the temperature below 10°C. The mixture was maintained below 10°C for 30 minutes. During approximately 20 minutes, water (408 g) was slowly added. Heptane (428.2 g) was added and the mixture was heated to room temperature. The aqueous phase was separated and the product was extracted with heptane.

The combined organic extract was washed with 25% ammonium hydroxide solution and purified water. The solvent was distilled at atmospheric pressure until approximately 3 volumes remained [relative to the feed amount of compound (5A)]. Tert-butyl methyl ether was added and the mixture was cooled to crystallize the product trestolone acetate. The product was separated by filtration and dried at 40–50 °C (yield: 78%; alpha:beta ratio = 99).
Chemical PropertiesBack Directory
[Melting point ]

111-114 °C
[Boiling point ]

447.6±45.0 °C(Predicted)
[density ]

1.11±0.1 g/cm3(Predicted)
[solubility ]

DMF: 30 mg/ml; DMSO: 25 mg/ml; Ethanol: 30 mg/ml
[form ]

A crystalline solid
[InChI]

InChI=1/C21H30O3/c1-12-10-14-11-15(23)4-5-16(14)17-8-9-21(3)18(20(12)17)6-7-19(21)24-13(2)22/h11-12,16-20H,4-10H2,1-3H3/t12-,16+,17-,18+,19+,20-,21+/s3
[InChIKey]

IVCRCPJOLWECJU-KHRPLIIWNA-N
[SMILES]

C[C@@H]1CC2=CC(=O)CC[C@]2([H])[C@@]2([H])CC[C@@]3([C@@H](OC(=O)C)CC[C@@]3([H])[C@]12[H])C |&1:1,9,11,15,16,23,25,r|
Hazard InformationBack Directory
[Description]

Trestolone Acetate is a synthetic and injectable anabolic and androgenic steroid (AAS) that has been derived from the famous steroid nandrolone (19-nortestosterone) that doesn’t have any medical uses but is very helpful for physique and performance enhancement purposes.
This steroid has firstly been described in 1963 and although there are many people searching and using Trestolone Acetate, is not as famous as many other steroids.
Trestolone Acetate is also known as MENT acetate or Ment Trestolone and this is a steroid considered really beneficial for purpose of bodybuilding and strength training. Known as a steroid that is more powerful than testosterone, Trestolone is believed to offer fast and effective results.
Ment Trestolone is believed to be the only steroid that can maintain a normal male physiology in a complete absence of testosterone, even including sexual life.
[Uses]

Trestolone is a synthetic anabolic-androgenic steroid (AAS) of the nandrolone (19-nortestosterone) group. In Vivo: Trestolone is used as trestolone acetate, which is administered via intramuscular injection and acts as a long-lasting prodrug of trestolone.
[Definition]

Trestolone acetate is a synthetic and injected anabolic–androgenic steroid (AAS) and a derivative of nandrolone (19-nortestosterone) which was never marketed. It is an androgen ester – specifically, the C17 acetate ester of [DB05830].
[Side effects]

Trestolone Acetate is quite obvious to offer negative side effects when is considered to be about 10 times more potent than testosterone. Side effects are only possible and they can be well reduced or completely avoided if you know how to use the compound properly.
For example, if you would use a PCT plan at the end of the cycle all along with various meds (like Aromatase Inhibitors) and different cycle supporting supplements, without exceeding cycle length and dosage then you would be fine in most cases (unless you have low tolerance or pre existent health issues).
Side effects include those of estrogen related (since it aromatizes) and the obvious androgen related ones. All in all, side effects include:
Acne
Hair loss
Water retention
Hypertension
Gynecomastia
Aggression
Suppression
Negative effects on lipids
Affects cardiovascular health and others
Remember to use Ment Trest properly if you want to avoid the side effects, because an improper use is almost guaranteeing getting negative side effects.
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