| Identification | More | [Name]
4-Methoxypyridine | [CAS]
620-08-6 | [Synonyms]
4-METHOXYPYRIDINE
METHYL PYRIDIN-4-YL ETHER
gamma-Methoxypyridine
4-methoxypridine
Pyridine, 4-methoxy-
4-METHOXYPYRIDINE, 98+% | [EINECS(EC#)]
210-624-7 | [Molecular Formula]
C6H7NO | [MDL Number]
MFCD00674049 | [Molecular Weight]
109.13 | [MOL File]
620-08-6.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless to slightly yellow liquid | [Melting point ]
4 °C
| [Boiling point ]
108-111 °C/65 mmHg (lit.) | [density ]
1.075 g/mL at 25 °C(lit.) | [refractive index ]
1.518-1.522
| [Fp ]
74 °C
| [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [solubility ]
DMSO (Slightly), Methanol (Slightly) | [form ]
Liquid | [pka]
6.58(at 25℃) | [color ]
Clear colorless to slightly yellow | [Specific Gravity]
1.075 | [BRN ]
108211 | [InChI]
InChI=1S/C6H7NO/c1-8-6-2-4-7-5-3-6/h2-5H,1H3 | [InChIKey]
XQABVLBGNWBWIV-UHFFFAOYSA-N | [SMILES]
C1=NC=CC(OC)=C1 | [CAS DataBase Reference]
620-08-6(CAS DataBase Reference) | [NIST Chemistry Reference]
Pyridine, 4-methoxy-(620-08-6) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin .
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S37/39:Wear suitable gloves and eye/face protection .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection . | [WGK Germany ]
3 | [HS Code ]
29333990 | [Storage Class]
10 - Combustible liquids | [Hazard Classifications]
Eye Irrit. 2
Skin Irrit. 2
STOT SE 3 |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless to slightly yellow liquid | [Uses]
4-Methoxypyridine, is used as a building block for the synthesis of some biologically active compounds. It is used for the preparation of a new series of benzoylated N-ylides as protein farnesyltransferase inhibitors. | [General Description]
4-Methoxypyridine has been prepared from 4-methoxypyridine-N-oxide, via catalytic hydrogenation. Ortho lithiation of 4-methoxypyridine using mesityllithium as the metalating base has been studied. | [Synthesis]
At room temperature, (50mmo1) 4-methoxypyridine-N-oxide was dissolved in 50mL acetonitrile solution, then 1.01g (55mmo1) tritiated cyanogen chloride (TCT) was added to the reaction solution in batches, and the reaction was tracked by TCL, and at the en |
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