| Identification | Back Directory | [Name]
3-nitro-N-(8-quinolinyl)benzamide | [CAS]
62802-77-1 | [Synonyms]
WAY-302159
3-nitro-N-(8-quinolinyl)benzamide
3-Nitro-N-(quinolin-8-yl)benzamide
Inhibitor,VEGFR,quinoline amide,inhibit,WAY 302159,HUVEC,Vascular endothelial growth factor receptor,WAY302159 | [Molecular Formula]
C16H11N3O3 | [MOL File]
62802-77-1.mol | [Molecular Weight]
293.277 |
| Chemical Properties | Back Directory | [storage temp. ]
Store at -20°C | [solubility ]
DMSO : 20 mg/mL (68.19 mM; ultrasonic and warming and heat to 60°C) | [form ]
Solid | [color ]
Light brown to brown |
| Hazard Information | Back Directory | [Uses]
VEGFR-2-IN-29 (Compound 5) is a VEGFR-2 inhibitor with an IC50 of 16.5 nM[1]. | [IC 50]
VEGFR-2: 16.5 nM (IC50) | [References]
[1] Yang Y, et al. Design, synthesis and biological evaluation of quinoline amide derivatives as novel VEGFR-2 inhibitors. Bioorg Med Chem Lett. 2010 Nov 15;20(22):6653-6. DOI:10.1016/j.bmcl.2010.09.014 |
|
|