| Identification | Back Directory | [Name]
Quinazoline, 4-[(4-bromophenyl)methoxy]- | [CAS]
737818-56-3 | [Synonyms]
WAY-340935
4-((4-Bromobenzyl)oxy)quinazoline
Quinazoline, 4-[(4-bromophenyl)methoxy]- | [Molecular Formula]
C15H11BrN2O | [MOL File]
737818-56-3.mol | [Molecular Weight]
315.16 |
| Chemical Properties | Back Directory | [Boiling point ]
455.0±25.0 °C(Predicted) | [density ]
1.494±0.06 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 63 mg/mL (199.90 mM);Ethanol: 3 mg/mL (9.52 mM) | [form ]
Solid | [pka]
2.66±0.30(Predicted) | [color ]
White to off-white | [Water Solubility ]
Water: Insoluble |
| Hazard Information | Back Directory | [Uses]
VEGFR2-IN-2 (compound 6e) is a potent and selective VEGFR2 inhibitor with an IC50 of 19.32 nM. VEGFR2-IN-2 can be used for researching | [Biological Activity]
WAY-340935 (VEGFR2-IN-2) can inhibit the function of VEGFR2 and the anti-proliferative activity against the H460 cell line is produced partly by interaction of VEGFR protein. | [IC 50]
VEGFR2: 19.32 nM (IC50) | [storage]
Store at -20°C | [References]
[1] Sun J, et al. Org Biomol Chem. 2013 Nov 28;11(44):7676-86. |
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