| Identification | Back Directory | [Name]
Azido-PEG4-NHBoc | [CAS]
642091-68-7 | [Synonyms]
Boc-NH-PEG3-N3
N3-PEG3-NH-BOC
Azido-PEG3-NHBoc
Azido-PEG4-NHBoc
Boc-N-Amido-PEG3-N3
BocNH-PEG3-CH2CH2N3
Boc-N-Amido-PEG3-Azide
t-Boc-N-Amido-PEG3-Azide
1-Boc-amine-11-azido-3,6,9-trioxaundecane
tert-butyl (2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)carbamate
tert-Butyl N-(2-{2-[2-(2-azidoethoxy)ethoxy]ethoxy}ethyl)carbamate
5,8,11-Trioxa-2-azatridecanoic acid, 13-azido-, 1,1-dimethylethyl ester | [Molecular Formula]
C13H26N4O5 | [MDL Number]
MFCD22056317 | [MOL File]
642091-68-7.mol | [Molecular Weight]
318.38 |
| Hazard Information | Back Directory | [Description]
t-Boc-N-Amido-PEG3-azide is a PEG reagent containing an azide group and Boc-protected amino group, it is reactive with alkyne, BCN, DBCO via Click Chemistry. The Boc group can be deprotected under mild acidic conditions to form the free amine. | [Uses]
Boc-N-Amido-PEG3-azide is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Boc-N-Amido-PEG3-azide is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [Definition]
ChEBI: Tert-Butyl (2-(2-(2-(2-azidoethoxy)ethoxy)ethoxy)ethyl)carbamate is a carbamate ester. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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