| Identification | More | [Name]
1-[2-(2,4-Dichlorophenyl)-n-pentyl]-1H-1,2,4-triazole | [CAS]
66246-88-6 | [Synonyms]
1-[2-(2,4-Dichlorophenyl)-n-pentyl]-1H-1,2,4-triazole
1-[2-(2,4-DICHLOROPHENYL)PENTYL]-1,2,4-TRIAZOLE
1-[2-(2,4-DICHLOROPHENYL)PENTYL]-1H-1,2,4-TRIAZOLE
PENCONAZOL
PENCONAZOLE
4-triazole,1-(2-(2,4-dichlorophenyl)pentyl)-1h-2
cga71818
onmex
topasc
topasmz
topaze
topazec
PENCONAZOL PESTANAL
PENCONAZOLE 98+%
1H-1,2,4-Triazole, 1-2-(2,4-dichlorophenyl)pentyl-
penconazole (bsi,iso)
Pine gel
Topas | [EINECS(EC#)]
266-275-6 | [Molecular Formula]
C13H15Cl2N3 | [MDL Number]
MFCD00078737 | [Molecular Weight]
284.18 | [MOL File]
66246-88-6.mol |
| Chemical Properties | Back Directory | [Melting point ]
58.5 °C | [Boiling point ]
436.06°C (rough estimate) | [density ]
1.2556 (rough estimate) | [vapor pressure ]
3.7 x l0-4 Pa (25 °C) | [refractive index ]
1.6300 (estimate) | [Fp ]
100 °C | [storage temp. ]
0-6°C | [solubility ]
DMSO: 100 mg/mL (351.89 mM) | [form ]
neat | [pka]
2.80±0.10(Predicted) | [Water Solubility ]
73 mg l-1 (25 °C) | [color ]
White | [BRN ]
541488 | [Henry's Law Constant]
6.9×102 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) | [Major Application]
agriculture
environmental | [InChI]
1S/C13H15Cl2N3/c1-2-3-10(7-18-9-16-8-17-18)12-5-4-11(14)6-13(12)15/h4-6,8-10H,2-3,7H2,1H3 | [InChIKey]
WKBPZYKAUNRMKP-UHFFFAOYSA-N | [SMILES]
CCCC(Cn1cncn1)c2ccc(Cl)cc2Cl | [LogP]
3.660 (est) | [CAS DataBase Reference]
66246-88-6(CAS DataBase Reference) | [EPA Substance Registry System]
66246-88-6(EPA Substance) |
| Safety Data | Back Directory | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes . | [RIDADR ]
UN 3077 9 / PGIII | [WGK Germany ]
2 | [RTECS ]
XZ4615000 | [HS Code ]
29339900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Aquatic Acute 1
Aquatic Chronic 1
Repr. 2 | [Toxicity]
LD50 skn-rat: >3 g/kg DOVEAA 38,195,84 |
| Hazard Information | Back Directory | [Chemical Properties]
Pentoxystrobin pure product is white powdery solid, melting point 60.3~61℃. Boiling point:>360°C, 99.2°C (1.9 Pa). Vapor pressure:0.17mPa(20℃),0.37mPa(25℃). Relative density 1.3. partition coefficient Kow lgP= 3.72( pH 5.7,20°C). Henry's constant 6.6×10-4Pa-m3/mol (calculated). Solubility in water 73 mg/L (25°C). Solubility in other solvents (25°C, g/L): ethanol 730, acetone 770, n-octanol 400, toluene 610, n-hexane 24. pH 1~13 hydrolytically stable; stable when heated to 350°C. | [Uses]
Penconazole is an conazole based fungicide that works by inhibiting cell membrane ergosterol biosynthesis, thus stopping the development of fungi. | [Uses]
Penconazole is used for the control of powdery mildew,
pome fruit scab and other pathogenic Ascomycetes, Basidiomycetes and
Deuteromycetes on vines, cucurbits, pome fruit, stone fruit, ornamentals,
hops, tobacco and vegetables. | [Definition]
ChEBI: 1-[2-(2,4-dichlorophenyl)pentyl]1,2,4-triazole is a member of the classof triazoles that is 1,2,4-triazole substituted at position 1 by a 2-(2,4-dichlorophenyl)pentyl group. It is a dichlorobenzene and a member of triazoles. | [Production Methods]
Penconazole is synthesised through a multi-step chemical process starting with 2-(2,4-dichlorophenyl)pentanol. In one method, the compound is first brominated to form a reactive bromide intermediate. The bromide then undergoes a condensation reaction with 1,2,4-triazole under alkaline conditions, typically using sodium hydroxide, to form the penconazole molecule. An alternative synthesis involves esterifying the starting alcohol with concentrated sulphuric acid and using 4-methyl-2-pentanone as a water-carrying agent, followed by reaction with triazole. The final product is purified through washing, phase separation, and crystallisation, yielding high-purity penconazole. | [Agricultural Uses]
Fungicide: Penconazole is a systemic fungicide used to control
powdery mildew. It is used on apples and grapes and
other fruits, hops, tobacco, ornamentals and on vegetables.
Not currently registered in the U.S. Reported to be used in
most European countries. Currently, there are more than
30 global suppliers. | [Trade name]
AWARD®; CGA-71818®; ONMEX®;
TOPAS®; TOPAS-C®; TOPAS-MZ®; TOPAZ®;
TOPAZE®; TOPAZE-C®; TOPENCO 100EC® | [Mechanism of action]
Systemic with curative and protective action, acts by interfering with ergosterol biosynthesis | [Safety Profile]
Moderately toxic by ingestion and skin contact. When heated to decomposition it emits toxic vapors of NOx and Clí. | [Metabolic pathway]
Penconazole is metabolised in plants by hydroxylation of the propyl side
chain and conjugation or metabolism to triazolylalanine and triazolylacetic
acid. It is quite persistent in soils but degradation by sunlight
requires only a few days. It is eliminated rapidly from mammals. | [storage]
Store at -20°C | [Degradation]
Penconazole (1) is stable to hydrolysis at pH 1-13 and at temperatures up
to 350 °C. It is degraded in sunlight with a DT50 of 4 days in natural sunlight.
Its photochemical reactions have been studied. On irradiation with
light of wavelengths greater than 280 nm (high-pressure mercury lamp
with filter), the major reaction was the formation of a cyclised product (2)
(Scheme 1). Irradiation under the same conditions in isopropanol gave
mainly 2 and 3 (a dechlorinated product). After 8 hours, yields were 29.8%
of 2 and 12.3% of 3 respectively. The product 3 alone photodegraded
only slowly but 2 was completely photolysed within 3 hours to further
products, indicating its role as an intermediate in the photolytic pathways
(Schwack and Hartmann, 1992, 1994). In the presence of isopropanol,
photodehalogenation of 3 to 4 competed with substitution of a
solvent molecule to give a low yield ( | [Pesticide Type]
Fungicide |
|
| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
|