| Identification | More | [Name]
Flutriafol | [CAS]
76674-21-0 | [Synonyms]
alpha-(2-fluorophenyl)-alpha-(4-fluorophenyl)-1h-1,2,4-triazole-1-ethanol
ATOUT(R)
CINCIT(R)
FLUTRIAFOL
IMPACT
IMPACT(R)
(RS)-1-(2-Fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol
VINCIT
4-triazole-1-ethanol,alpha-(2-fluorophenyl)-alpha-(4-fluorophenyl)-1h-2
pp450
r152450
(RS)-2,4-difluoro-α-(1H-1,2,4-triazol-1-ylmethyl)benzhydryl alcohol
FLUTRIAFOL SOLUTION 100 NG/MYL IN ACETON ITRILE, PESTANAL
1H-1,2,4-Triazole-1-ethanol, .alpha.-(2-fluorophenyl)-.alpha.-(4-fluorophenyl)-
flutriafol (ansi,bsi,iso)
flutriafol solution
FLUTRIAFOLE
ALTOSUPER
1-(2-Fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol | [Molecular Formula]
C16H13F2N3O | [MDL Number]
MFCD00144319 | [Molecular Weight]
301.29 | [MOL File]
76674-21-0.mol |
| Chemical Properties | Back Directory | [Appearance]
solid | [Melting point ]
130° | [Boiling point ]
506.5±60.0 °C(Predicted) | [density ]
1.3015 (estimate) | [vapor pressure ]
7.1 x l0-9 Pa (20 °C) | [Fp ]
2 °C | [storage temp. ]
0-6°C | [solubility ]
Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) | [form ]
neat | [pka]
11.60±0.29(Predicted) | [Water Solubility ]
130 mg l-1 (pH 7,20 °C) | [color ]
White to Off-White | [Stability:]
Stable. Incompatible with strong oxidizing agents. | [Merck ]
13,4240 | [BRN ]
8155287 | [Henry's Law Constant]
6.1×107 mol/(m3Pa) at 25℃, Duchowicz et al. (2020) | [Major Application]
agriculture
environmental | [InChI]
1S/C16H13F2N3O/c17-13-7-5-12(6-8-13)16(22,9-21-11-19-10-20-21)14-3-1-2-4-15(14)18/h1-8,10-11,22H,9H2 | [InChIKey]
JWUCHKBSVLQQCO-UHFFFAOYSA-N | [SMILES]
OC(Cn1cncn1)(c2ccc(F)cc2)c3ccccc3F | [LogP]
2.290 | [CAS DataBase Reference]
76674-21-0(CAS DataBase Reference) | [NIST Chemistry Reference]
Flutriafol(76674-21-0) | [EPA Substance Registry System]
76674-21-0(EPA Substance) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn,F | [Risk Statements ]
R22:Harmful if swallowed.
R36:Irritating to the eyes.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed .
R11:Highly Flammable. | [Safety Statements ]
S22:Do not breathe dust .
S24/25:Avoid contact with skin and eyes .
S36:Wear suitable protective clothing .
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [RIDADR ]
UN 1648 3/PG 2 | [WGK Germany ]
3 | [RTECS ]
XZ4825000 | [HS Code ]
29339900 | [Storage Class]
11 - Combustible Solids | [Hazard Classifications]
Acute Tox. 4 Oral
Aquatic Chronic 2 | [Toxicity]
LD50 male, female rats (mg/kg): 1140, 1480 orally; rats, rabbits: >1000, >2000 percutaneously (Skidmore) |
| Hazard Information | Back Directory | [Description]
Flutriafol is a commonly used curative and preventative fungicide. It is moderately soluble in water, tends to be persistent in soil systems and is often stable in aquatic systems. It is moderately mobile and so may leach to groundwaters under certain conditions. It is moderately toxic to most biodiversity including honeybees and earthworms. It may be a development and/or reproduction toxin. | [Description]
Little data is available for the isomer but is available for the isomeric mixture. Flutriafol is a commonly used curative and preventative fungicide. It is moderately soluble in water, tends to be persistent in soil systems and is often stable in aquatic systems. It is moderately mobile and so may leach to groundwaters under certain conditions. It is moderately toxic to most biodiversity including honeybees and earthworms. It may be a development and/or reproduction toxin, | [Description]
Little information is available for the specific isomer but is for the isomeric mixture. Flutriafol is a commonly used curative and preventative fungicide. It is moderately soluble in water, tends to be persistent in soil systems and is often stable in aquatic systems. It is moderately mobile and so may leach to groundwaters under certain conditions. It is moderately toxic to most biodiversity including honeybees and earthworms. It may be a development and/or reproduction toxin. | [Chemical Properties]
solid | [Uses]
Agricultural fungicide. | [Uses]
Flutriafol is a systemic fungicide of the triazole class. Flutriafol has broad spectrum fungicidal activity and is used to control effectively cereal powdery mildew, cloud disease, leaf spot disease a
nd rust disease. | [Uses]
Flutriafol is used to control a wide variety of leaf and ear diseases
in cereals. It is also used in seed treatment formulations to control the
major soil-borne and seed-borne diseases of cereals. | [Definition]
ChEBI: 1-(2-fluorophenyl)-1-(4-fluorophenyl)-2-(1H-1,2,4-triazol-1-yl)ethanol is a tertiary alcohol that is ethanol in which one of the hydrogens at position 1 is replaced by an p-fluorophenyl group, the other hydrogen at position 1 is replaced by a p-fluorophenyl group, and one of the hydrogens at position 2 is replaced by a 1H-1,2,4-triazol-1-yl group. It is a member of triazoles, a tertiary alcohol and a member of monofluorobenzenes. | [Mechanism of action]
Broad-spectrum, systemic, contact action with eradicant and protective properties. Sterol biosynthesis inhibitor. | [Synthesis]
Anhydrous potassium fluoride was reacted with 2,3,4,5-tetrachloronitrobenzene in anhydrous dimethylformamide at 140°C for 15 hours to obtain 2,4-difluoro-3,5-dichloronitrobenzene, and then the reaction was carried out in acetic acid at 95-100°C for 8 hour | [Metabolic pathway]
Flutriafol is stable to hydrolysis and to light and it is persistent in soils. In
crops, the metabolites identified were derivatives of triazole. | [Degradation]
Flutriafol, 1, is stable to hydrolysis at pH 5,7 and 9 in water at 50 °C over
a period of 30 days in the dark.
[14C-friazole]Flutriafoaln d [14C-carbinol]flutriafol were applied at a rate
equivalent to 94 g ai ha-1 to samples of dry sandy loam soil distributed as
a thin layer on 10 cm diameter glass plates. Samples were exposed to
natural sunlight for 30 days or to alternating periods of 'black light' and
darkness for 7 days. Recovery was 60-47% of applied radioactivity after
7 days artificial illumination and 74-85% after exposure to natural sunlight.
All degradation products accounted for ＜5 %of the total applied
radioactivity (PSD, 1996). | [Pesticide Type]
Fungicide |
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