| Identification | More | [Name]
3-Carboxy-4-nitrophenyl disulfide | [CAS]
69-78-3 | [Synonyms]
2,2'-DINITRO-5,5'-DITHIODIBENZOIC ACID
3-CARBOXY-4-NITROPHENYL DISULFIDE
5-[(3-CARBOXY-4-NITROPHENYL)DITHIO]-2-NITROBENZOIC ACID
5,5'-DITHIOBIS(2-NITROBENZOIC ACID)
5,5-DITHIO-BIS(2-NITROBENZOIC ACID)
6,6'-DINITRO-3,3'-DITHIODIBENZOIC ACID
BIS(3-CARBOXY-4-NITROPHENYL) DISULFIDE
DTNB
ellmann's reagent
ELLMAN'S REAGENT
ELLMANS' REAGENT
2,2’-dinitro-5,5’-dithiodibenzoesaeure
3,3’-dithiobis(6-nitro-benzoicaci
3,3’-dithiobis(6-nitrobenzoicacid)
3,3’-dithiobis[6-nitro-benzoicaci
5,5’-dithiobis(2-nitrobenzoic
dithionitrobenzoicacid
Bis(3-carboxy-4-nitrophenyl) disulphide~3-Carboxy-4-nitrophenyl disulphide~Ellmans
Ellmanns
5,5'-Dithobis(2-Nitrobenzoic Acid) | [EINECS(EC#)]
200-714-4 | [Molecular Formula]
C14H8N2O8S2 | [MDL Number]
MFCD00007140 | [Molecular Weight]
396.35 | [MOL File]
69-78-3.mol |
| Chemical Properties | Back Directory | [Appearance]
Crystalline | [Melting point ]
240-245 °C (dec.)(lit.)
| [Boiling point ]
671.9±55.0 °C(Predicted) | [bulk density]
290kg/m3 | [density ]
1.67 | [refractive index ]
1.6900 (estimate) | [storage temp. ]
Store at RT. | [solubility ]
Do you have solubility information on this product that you would like to share | [form ]
Yellow solid | [pka]
1.57±0.25(Predicted) | [color ]
Pale Yellow to Light Yellow | [Stability:]
Stable. Incompatible with strong bases, strong oxidizing agents. | [Water Solubility ]
Soluble in water and ethanol. | [Detection Methods]
HPLC,NMR | [Merck ]
3551 | [BRN ]
1896821 | [InChIKey]
KIUMMUBSPKGMOY-UHFFFAOYSA-N | [CAS DataBase Reference]
69-78-3(CAS DataBase Reference) | [EPA Substance Registry System]
69-78-3(EPA Substance) |
| Hazard Information | Back Directory | [Chemical Properties]
Crystalline | [Uses]
5,5′-Dithiobis(2-nitrobenzoic acid) is an membrane-impermeant thiol/disulfide exchange blocker. It is also used to quantify the number or concentration of thiol groups in a sample.
| [Definition]
ChEBI: An organic disulfide that results from the formal oxidative dimerisation of 2-nitro-5-thiobenzoic acid. An indicator used to quantify the number or concentration of thiol groups. | [General Description]
5,5′-Dithiobis(2-nitrobenzoic acid) is also called DTNB or Ellman′s reagent. It is a water soluble reagent, which interacts with thiol groups, and can be used conveniently at neutral pH. Thiolate anion (RS-) reacts with Ellman′s reagent (DTNB2-), to produce 2-nitro-5-thiobenzoate anion (TNB2-) and one mixed disulfide (R-S-TNB-). TNB2- has a high molar absorption coefficient, and absorbs at 412nm. This absorption is independent of pH, at pH> 7.3. | [Biological Activity]
Cell permeable: no''Primary Target
Useful in photometric determination of thiols''Product does not compete with ATP.''Reversible: no |
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