| Identification | Back Directory | [Name]
MD 770222 | [CAS]
70133-35-6 | [Synonyms]
MD 770222
3-[[4-[5-(Hydroxymethyl)-2-oxo-3-oxazolidinyl]phenoxy]methyl]benzonitrile | [Molecular Formula]
C18H16N2O4 | [MOL File]
70133-35-6.mol | [Molecular Weight]
324.33 |
| Hazard Information | Back Directory | [Description]
MD 770222 is a metabolite of cimoxatone that inhibits the deamination of noradrenaline. | [Uses]
MD 770222, a major plasma O-demethyl metabolite of Cimoxatone (HY-15386), is an orally active, selective and reversible MAO A inhibitor. MD 770222 shows less potent than Cimoxatone[1]. | [References]
[1] V Rovei, et al. Pharmacokinetic and relative bioavailability studies of cimoxatone in humans. Int J Clin Pharmacol Ther Toxicol. 1984 Jan;22(1):56-62. PMID:6698662 |
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