| Identification | More | [Name]
(1-METHYL-4-PIPERIDINYL)METHANAMINE | [CAS]
7149-42-0 | [Synonyms]
(1-METHYL-4-PIPERIDINYL)METHANAMINE
1-METHYL-PIPERIDIN-4-METHYLAMINE
(1-METHYLPIPERIDIN-4-YL)METHANAMINE
[(1-METHYLPIPERIDIN-4-YL)METHYL]AMINE
4-AMINOMETHYL-1-METHYLPIPERIDINE
AKOS B025002
ART-CHEM-BB B025002
BUTTPARK 145\06-16
C-(1-METHYL-PIPERIDIN-4-YL)-METHYLAMINE
CHEMBRDG-BB 4103003
TIMTEC-BB SBB009719
1-methylpiperidine-4-methylamine
(1-Methyl-4-piperidinyl)methaneamine
(1-Methylpiperidine-4-yl) methylamine
(1-Methyl pyperidin-4-yl)methyl amine
(1-methyl-4-piperidnyl)methanamine
(1-methyl-4-piperidinyl)methylamine
4-Aminomethyl-1-methylpiperidine ,97%
1-Methyl-4-piperidinemethanamine
1-Methyl-4-(aminomethyl)piperidine | [EINECS(EC#)]
230-477-2 | [Molecular Formula]
C7H16N2 | [MDL Number]
MFCD05022430 | [Molecular Weight]
128.22 | [MOL File]
7149-42-0.mol |
| Chemical Properties | Back Directory | [Melting point ]
0°C | [Boiling point ]
80 °C | [density ]
0.901±0.06 g/cm3(Predicted) | [Fp ]
0°C | [storage temp. ]
Keep in dark place,Sealed in dry,Room Temperature | [form ]
liquid | [pka]
10.13±0.29(Predicted) | [color ]
Pale yellow | [Detection Methods]
GC | [InChI]
InChI=1S/C7H16N2/c1-9-4-2-7(6-8)3-5-9/h7H,2-6,8H2,1H3 | [InChIKey]
AGTPSAZJSOQXHJ-UHFFFAOYSA-N | [SMILES]
N1(C)CCC(CN)CC1 | [CAS DataBase Reference]
7149-42-0(CAS DataBase Reference) | [Storage Precautions]
Moisture sensitive;Store under nitrogen |
| Safety Data | Back Directory | [Symbol(GHS) ]
  
GHS02,GHS05,GHS07 | [Signal word ]
Danger | [Hazard statements ]
H226-H302-H314 | [Precautionary statements ]
P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P370+P378-P403+P235 | [Hazard Codes ]
C,Xi | [Risk Statements ]
R34:Causes burns.
R20/22:Harmful by inhalation and if swallowed . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S23:Do not breathe gas/fumes/vapor/spray (appropriate wording to be specified by the manufacturer) . | [RIDADR ]
2735 | [WGK Germany ]
1 | [Hazard Note ]
Corrosive | [HazardClass ]
IRRITANT | [HS Code ]
29333990 | [Storage Class]
3 - Flammable liquids | [Hazard Classifications]
Acute Tox. 4 Oral
Eye Dam. 1
Flam. Liq. 3
Skin Corr. 1C |
| Hazard Information | Back Directory | [Chemical Properties]
Colourless liquid | [Uses]
(1-methyl-4-piperidinyl)methanamine is a reagent used in the synthesis of novel indole-carboxamides which are inhibitors of neurotropic alphavirus. | [Synthesis]
1-Methylisonipecotamide (6.75g, 47. 5MMOLES) was dissolved in anhydrous THF (350mL), and the resulting mixture was added in portions to a stirred slurry of lithium aluminum hydride (1.8g, 47. 5mmoles) in anhydrous THF (100 mL) at 0 ℃ under nitrogen. The mixture was stirred at 0 ℃ for 30min and then heated at 66 ℃ for 25h under nitrogen. Distilled water (1.88 mL) was added dropwise to the stirred mixture at 0 ℃, followed by 20 percent aqueous sodium hydroxide (1.42 mL), and then distilled water (6.75mL), and the mixture was stirred for 15 min. The mixture was filtered, and the solids were washed with THF and dichloromethane. The combined filtrates were evaporated to dryness and chromatographed on a silica gel column (30x5 cm) using 15 percent-20 percent (10 percent CONC. ammonium hydroxide in METHANOL)-DICHLOROMETHANE as the eluant to give (1-Methyl-4-piperidinyl)methanamine (0.678g, 11percent).
| [References]
[1] Journal of Medicinal Chemistry, 2003, vol. 46, # 7, p. 1116 - 1119
[2] Patent: WO2004/22561, 2004, A1. Location in patent: Page 110-11 |
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| Company Name: |
J & K SCIENTIFIC LTD.
|
| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
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