| Identification | Back Directory | [Name]
Cefmenoxime hydrochloride | [CAS]
75738-58-8 | [Synonyms]
Cemix
Tacef
Cefmax
Bestron
Bestcall
Abbott 50192
CEFMENOXIME HCL
CefMenoxiMe SodiuM
SCE-1365(free acid)
sce1365hydrochloride
ab50912hemihydrochloride
CEFMENOXIME HYDROCHLORIDE
2Cefmenoxime·Hydrochloride
Hydrochloride (syn-isomer)
SCE-1365 hemihydrochloride
cefmenoximehemihydrochloride
CefMenoxiMe HCL Sterile (pure)
Cefmenoxime Hydrochloride (350 mg)
Cefmenoxime hydrochloride USP/EP/BP
hydrochloride(2:1),(6r-(6-alpha,7-beta(z)))-o
CEFMENOXIME HEMIHYDROCHLORIDE;SCE-1365 HEMIHYDROCHLORIDE
)(methoxyimino)acetyl)amino)-3-(((1-methyl-1h-tetrazol-5-yl)thio)methyl)-8-ox
7beta-[2-(2-Aminothiazol-4-yl)-(Z)-2-(methoxyiminoacetamido)]-3-[(1-methyl-1H-tetrazol-5-yl)thiomethyl]ceph-3-em-4-carboxylic acid hemihydrochloride
7-[[(2-Amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hemihydrochloride
7-[[2-(2-amino-4-thiazolyl)-2-methoxyimino-1-oxoethyl]amino]-3-[[(1-methyl-5-tetrazolyl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride
8-[2-(2-amino-1,3-thiazol-4-yl)-2-methoxyimino-acetyl]amino-4-[(1-methyltetrazol-5-yl)sulfanylmethyl]-7-oxo-2-thia-6-azabicyclo[4.2.0]oct-4-ene-5-carboxylic acid hydrochloride (2:1)
(6R)-7α-[[(2-Amino-4-thiazolyl)[(Z)-methoxyimino]acetyl]amino]-3-[[(1-methyl-1H-tetrazole-5-yl)thio]methyl]-8-oxo-5-thia-1-azabicyclo[4.2.0]octa-2-ene-2-carboxylic acid·0.5hydrochloride
(6R,7R)-7-[[(2Z)-(2-AMino-4-thiazolyl)(MethoxyiMino)acetyl]aMino]-3-[[(1-Methyl-1H-tetrazol-5-yl)thio]Methyl]-8-oxo-5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic Acid HeMihydrochloride
(6R,7R)-7-((Z)-2-(2-aminothiazol-4-yl)-2-(methoxyimino)acetamido)-3-(((1-methyl-1H-tetrazol-5-yl)thio)methyl)-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid hydrochloride(2:1)
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2Z)-(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, hydrochloride (2:1), (6R,7R)-
5-Thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid, 7-[[(2-amino-4-thiazolyl)(methoxyimino)acetyl]amino]-3-[[(1-methyl-1H-tetrazol-5-yl)thio]methyl]-8-oxo-, hydrochloride (2:1), [6R-[6α,7β(Z)]]- | [EINECS(EC#)]
278-299-4 | [Molecular Formula]
C32H35ClN18O10S6 | [MDL Number]
MFCD01750403 | [MOL File]
75738-58-8.mol | [Molecular Weight]
1059.58 |
| Chemical Properties | Back Directory | [Melting point ]
>175°C (dec.) | [storage temp. ]
Inert atmosphere,2-8°C | [solubility ]
DMSO (Slightly, Heated), Methanol (Slightly) | [form ]
Solid | [color ]
Off-White to Pale Yellow | [InChIKey]
HZYJYGJIOCXOTH-AJVJENPNNA-N | [SMILES]
C(C1=C(CS[C@]2([H])[C@H](NC(=O)/C(/C3N=C(N)SC=3)=N\OC)C(=O)N12)CSC1=NN=NN1C)(=O)O.Cl |&1:5,7,r| |
| Hazard Information | Back Directory | [Description]
Cef menoxime hydrochloride is a third generation cephalosporin antibiotic.
Structurally, it possesses the (1-methyl-lH-tetrazol-5-yl)thiomethyl moiety in
the 3-position; like several other compounds containing this structural element
(moxalactam, cefoperazone, cefamandol), bleeding linked to vitamin K interaction
has been reported. Cefmenoxime has activity similar to cefotiuime, ceftizoxime
and moxalactam against E.coli, C. diversus, Klebsiella, P. Mirabilis, Salmonella,
Shigella, Neiseria spp., S. pyogenes, S. Pneumoniae, and g. influenzae. It is
relatively ineffective against Pseudomonas and Bacteroidea. | [Originator]
Takeda (Japan) | [Uses]
A third generation cephalosporin antibiotic with strong antimicrobial activities against Streptococcus pneumoniae, Haemophilus influenzae and Moraxella subgenus Branhamella catarrhalis that were 3 major aerobic bacteria from sinusitis. | [Uses]
antibacterial | [Definition]
ChEBI: The hemihydrochloride salt of cefmenoxime. | [Brand name]
Cefmax (TAP);TACEF;BESTCALL. |
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