| Identification | More | [Name]
N-NITROSO-N-ETHYLUREA | [CAS]
759-73-9 | [Synonyms]
1-ETHYL-1-NITROSOUREA
1-NITROSO-1-ETHYLUREA
ENU
N-ETHYL-N-NITROSOUREA
N-NITROSOETHYLUREA
N-NITROSO-N-ETHYLUREA
1-(Aminocarbonyl)-1-ethyl-2-oxohydrazine
1-Ethyl-1-nitrosomocovina
1-ethyl-1-nitroso-ure
Aenh
Aethylnitroso-harnstoff
anh
Carbamide, N-ethyl-N-nitroso-
Ethylnitrosourea
N-Ethylnitrosourea
n-ethyl-n-nitroso-carbamid
n-ethyl-n-nitroso-ure
NEU
Nitrosoethylurea
NSC 45403 | [EINECS(EC#)]
212-072-2 | [Molecular Formula]
C3H7N3O2 | [MDL Number]
MFCD00053635 | [Molecular Weight]
117.11 | [MOL File]
759-73-9.mol |
| Chemical Properties | Back Directory | [Appearance]
N-Nitroso-N-ethyl urea is a pale yellow, crystalline
powder; freezing/melting point=103－104°C
(decomposes). Hazard identification (based on NFPA-704
M Rating System): Health 2; flammability 1; reactivity 0?.
Soluble in water; hydrolysis produces explosive gas. | [Melting point ]
103-1040C (dec) | [Boiling point ]
182℃ | [density ]
1.35 | [refractive index ]
1.4900 (estimate) | [Fp ]
64℃ | [storage temp. ]
−20°C
| [pka]
12.32±0.50(Predicted) | [Water Solubility ]
12.83g/L(room temperature) | [Stability:]
Unstable at RT, Contains approximately 40% Water, 2.0% Acetic Acid to stabilize | [CAS DataBase Reference]
759-73-9(CAS DataBase Reference) | [IARC]
2A (Vol. 17, Sup 7) 1987 | [EPA Substance Registry System]
N-Nitroso-N-ethylurea (759-73-9) |
| Safety Data | Back Directory | [Hazard Codes ]
T | [Risk Statements ]
R45:May cause cancer.
R61:May cause harm to the unborn child.
R20/21/22:Harmful by inhalation, in contact with skin and if swallowed . | [Safety Statements ]
S53:Avoid exposure-obtain special instruction before use .
S22:Do not breathe dust .
S36/37/39:Wear suitable protective clothing, gloves and eye/face protection .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) . | [RIDADR ]
UN 2811 6.1/PG 3
| [WGK Germany ]
3
| [RTECS ]
YT3150000
| [HazardClass ]
6.1(b) | [PackingGroup ]
III | [Safety Profile]
Confirmed carcinogen
with experimental carcinogenic,
neoplastigenic, tumorigenic, and teratogenic
data. Poison by ingestion, subcutaneous,
intraperitoneal, and intravenous routes.
Human mutation data reported. When
heated to decomposition it emits toxic
fumes of NOx. See also N-NITROSO
COMPOUNDS. | [Hazardous Substances Data]
759-73-9(Hazardous Substances Data) | [Toxicity]
LD50 i.v. in rats: 240 mg/kg (Druckrey) |
| Hazard Information | Back Directory | [General Description]
Yellow-pink crystals or off-white powder. Sensitive to light. | [Reactivity Profile]
N-NITROSO-N-ETHYLUREA(759-73-9) is highly reactive. Sensitive to moisture and light. Its stability in aqueous solutions is pH-dependent. Incompatible with water and nucleophilic reagents. Alkaline hydrolysis produces a highly explosive gas. . | [Air & Water Reactions]
Water soluble. Sensitive to moisture--stability in aqueous solutions depends on pH. | [Hazard]
Tumorigen, carcinogen, neoplastigen; teratogen; poison; toxic. | [Health Hazard]
ACUTE/CHRONIC HAZARDS: This compound is extremely unstable at high pH. It will decompose to extremely unstable decomposition products if acidic conditions are not maintained. When heated to decomposition it emits toxic fumes of nitrogen oxides. Decomposition products may be explosive. | [Potential Exposure]
Used as a chemical intermediate for
dyes and pharmaceuticals; a polymerization inhibitor during
the manufacture of vinyl monomers such as styrene; a
precursor of diazoethane; accelerator for rubber vulcanization. | [Fire Hazard]
Flash point data for this chemical are not available; however, N-NITROSO-N-ETHYLUREA is probably combustible. | [First aid]
If this chemical gets into the eyes, remove any
contact lenses at once and irrigate immediately for at least
15 minutes, occasionally lifting upper and lower lids. Seek
medical attention immediately. If this chemical contacts the
skin, remove contaminated clothing and wash immediately
with soap and water. Seek medical attention immediately.
If this chemical has been inhaled, remove from exposure,
begin rescue breathing (using universal precautions, including
resuscitation mask) if breathing has stopped and CPR if
heart action has stopped. Transfer promptly to a medical
facility. When this chemical has been swallowed, get medical
attention. Give large quantities of water and induce
vomiting. Do not make an unconscious person vomit. | [Shipping]
Toxic solids, organic, n.o.s., Hazard Class: 6.1;
Labels: 6.1-Poisonous materials, Technical Name Required.
UN3077 Environmentally hazardous substances, solid,
n.o.s., Hazard Class: 9; Labels: 9-Miscellaneous hazardous
material, Technical Name Required. | [Incompatibilities]
N-nitroso-N-ethylurea is highly reactive.
Sensitive to moisture and light. Its stability in aqueous
solutions is pH-dependent. Incompatible with water and
nucleophilic reagents. Alkaline hydrolysis produces a
highly explosive gas. This compound is extremely
unstable at high pH. It will decompose to extremely
unstable decomposition products if acidic conditions are
not maintained. Nitrated organics range from slight to
strong oxidizing agents. If mixed with reducing agents,
including hydrides, sulfides and nitrides, they may begin a
vigorous reaction. Reaction with | [Chemical Properties]
N-Nitroso-N-ethyl urea is a pale yellow, crystalline
powder; freezing/melting point=103－104°C
(decomposes). Hazard identification (based on NFPA-704
M Rating System): Health 2; flammability 1; reactivity 0?.
Soluble in water; hydrolysis produces explosive gas. | [Chemical Properties]
Orange Paste | [Waste Disposal]
Consult with environmental
regulatory agencies for guidance on acceptable disposal
practices. Generators of waste containing this contaminant
(≥100 kg/mo) must conform with EPA regulations
governing storage, transportation, treatment, and waste
disposal. | [Uses]
N-Nitroso-N-ethylurea has been used as a mutation-inducing agent. | [Uses]
A precursor of Diazoethane | [Uses]
Experimentally as mutagen; ethylating agent. | [Definition]
ChEBI: A member of the class of N-nitrosoureas that is urea in which one of the nitrogens is substituted by ethyl and nitroso groups. | [Biochem/physiol Actions]
DNA alkylating agent that is carcinogenic in many animal species. Induces benign and malignant tumors of numerous types, including the nervous tissue, stomach, esophagus, pancreas, respiratory tract, intestine, lymphoreticular tissues, skin, and kidney. | [Carcinogenicity]
N-Nitroso-N-ethylurea is reasonably anticipated to be a human carcinogen based on sufficient evidence of carcinogenicity from studies in experimental animals. |
|
| Company Name: |
Aemon Chemical
|
| Tel: |
0086-755-86198205 |
| Website: |
www.aemonchem.com |
| Company Name: |
Spectrum Chemical Manufacturing Corp.
|
| Tel: |
021-021-021-67601398-809-809-809 15221380277 |
| Website: |
www.spectrumchemical.com/oa_html/index.jsp?minisite=10020&respid=22372&language=us |
|