ChemicalBook--->CAS DataBase List--->58994-96-0

58994-96-0

58994-96-0 Structure

58994-96-0 Structure
IdentificationMore
[Name]

Ranimustine
[CAS]

58994-96-0
[Synonyms]

1-(2-chloroethyl)-1-nitroso-3-[[(2r,3s,4s,5r,6s)-3,4,5-trihydroxy-6-methoxy-oxan-2-yl]methyl]urea
RANIMUSTINE
RCL L16,919-6
Cymerin
MCNU
Methyl 6-[[[(2-chloroethyl)nitrosoamino]carbonyl]amino]-6-deoxy-α-D-glucopyranoside
NSC-0270516
Ranomustine
Thymerin
Methyl 6-[3-(2-chloroethyl)-3-nitrosoureido]-6-deoxy-α-D-glucopyranoside
[Molecular Formula]

C10H18ClN3O7
[MDL Number]

MFCD00866369
[Molecular Weight]

327.72
[MOL File]

58994-96-0.mol
Chemical PropertiesBack Directory
[Melting point ]

111-112°
[alpha ]

D20 +93.2° (c = 0.5 in methanol) (Kimura); D25 +73.2° (c = 0.3 in methanol) (Kimura, Sekine)
[CAS DataBase Reference]

58994-96-0(CAS DataBase Reference)
Raw materials And Preparation ProductsBack Directory
[Raw materials]

Acetic acid-->CATION STANDARD - SODIUM-->Activ Ester-->DARUTOSIDE
Hazard InformationBack Directory
[Description]

Ranimustine, a new nitrosourea derivative, is a water soluble antitumor agent with low hematological toxicity and diabetogenic effect. It is reportedly effective in the treatment of hematologic malignancies, especially the myeloproliferative disorders.
[Originator]

Tokyo Tanabe (Japan)
[Uses]

Glucocorticoid with low systemic absorption anti-inflammatory agent
[Definition]

ChEBI: Ranimustine is an organic molecular entity.
[Brand name]

Cymerine
Safety DataBack Directory
[Toxicity]

LD50 in male rats (mg/kg): 42 i.p., 42 i.v., 50 orally (Kimura)
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