| Identification | Back Directory | [Name]
Danshensu | [CAS]
76822-21-4 | [Synonyms]
Danshensu
Tanshinol
Salvianic aid A
dan shen suan a
SALVIANIC ACID A
Danshensu SodiuM
Danshensu 76822-21-4
Sodium Danshensu ,98%
SALVIANIC ACID A SODIUM SALT
3-(3,4-Dihydroxyphenyl)-D-lactic acid
β-(3,4-Dihydroxyphenyl)-D-lactic acid
D(+)β-(3,4-Dihydroxyphenyl)lacticacid
(r)-a,3,4-trihydroxybenzenepropanoic acid
3-(3',4'-Dihydroxyphenyl)-(2R)-lactic acid
Benzenepropanoic acid, α,3,4-trihydroxy-, (αR)-
(2R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoicaci
(R)-3-(3,4-Dihydroxyphenyl)-2-hydroxypropanoic acid
(R)-2-Hydroxy-3-(3,4-dihydroxyphenyl)propanoic acid
(R)-2-Hydroxy-3-(3,4-dihydroxyphenyl)propionic acid
(2R)-3-(3,4-dihydroxyphenyl)-2-hydroxypropanoic acid
Danshensu
(R)-a,3,4-Trihydroxybenzenepropanoic acid | [Molecular Formula]
C9H10O5 | [MDL Number]
MFCD09037393 | [MOL File]
76822-21-4.mol | [Molecular Weight]
198.17 |
| Chemical Properties | Back Directory | [Melting point ]
>210°C (dec.) | [Boiling point ]
481.5±40.0 °C(Predicted) | [density ]
1.546 | [storage temp. ]
under inert gas (nitrogen or Argon) at 2-8°C | [solubility ]
Water (Slightly) | [form ]
Solid | [pka]
3.82±0.10(Predicted) | [color ]
Light Beige | [InChI]
InChI=1/C9H10O5/c10-6-2-1-5(3-7(6)11)4-8(12)9(13)14/h1-3,8,10-12H,4H2,(H,13,14)/t8-/s3 | [InChIKey]
PAFLSMZLRSPALU-SBYBRXNCNA-N | [SMILES]
C(=O)(O)[C@H](O)CC1=CC=C(O)C(O)=C1 |&1:3,r| |
| Hazard Information | Back Directory | [Chemical Properties]
White crystals, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Salvia miltiorrhiza. | [Uses]
Danshensu increases production of collagenin Detroit 551 cells and attenuates the α-MSH-stimulated melanin production of B16 cells. Danshensu may be used as active ingredients in would healing, cosmetic treatments or treating hyperpigmentation. | [Definition]
ChEBI: (2R)-3-(3,4-dihydroxyphenyl)lactic acid is a (2R)-2-hydroxy monocarboxylic acid that is (R)-lactic acid substituted at position 3 by a 3,4-dihydroxyphenyl group. It is a (2R)-2-hydroxy monocarboxylic acid and a 3-(3,4-dihydroxyphenyl)lactic acid. It is a conjugate acid of a (2R)-3-(3,4-dihydroxyphenyl)lactate. | [in vivo]
Danshensu (Dan shen suan A; 25, 50, 100?mg/kg; oral administration daily for 7 continuous days or i.v. once) before SARS-CoV-2 S infection dose-dependently alleviates the pathological alterations in mice infected with SARS-CoV-2 S[1].
| Animal Model: | Adult BALB/c mice (male, 6-8 weeks, 20±2?g)[1] | | Dosage: | 25, 50, 100?mg/kg | | Administration: | Oral administration (daily for 7 continuous days) or i.v. (once) | | Result: | Could prevent SARS-CoV-2 S protein-induced acute lung inflammation.
Ameliorated inflammatory cytokines in serum and lung tissue.
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| Company Name: |
J & K SCIENTIFIC LTD.
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| Telephone: |
18210857532 18210857532 |
| Website: |
https://www.jkchemical.com |
| Company Name: |
China Langchem Inc.
|
| Telephone: |
0086-21-58956006 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList19141/0_EN.htm |
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