| Identification | More | [Name]
1,3-Dichloroisoquinoline | [CAS]
7742-73-6 | [Synonyms]
1,3-DICHLOROISOQUINOLINE
TIMTEC-BB SBB003563
4-(AMINOMETHYL)-4-HYDROXY-1-METHYLPIPERIDINE | [EINECS(EC#)]
627-814-4 | [Molecular Formula]
C9H5Cl2N | [MDL Number]
MFCD00034750 | [Molecular Weight]
198.05 | [MOL File]
7742-73-6.mol |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S36:Wear suitable protective clothing . | [WGK Germany ]
3
| [HS Code ]
29163990 |
| Hazard Information | Back Directory | [Chemical Properties]
White to brown crystalline powder | [Uses]
1,3-Dichloroisoquinoline may be used in the facile synthesis of 1,3,4-trisubstituted isoquinoline derivatives. | [Synthesis Reference(s)]
Journal of the American Chemical Society, 80, p. 5481, 1958 DOI: 10.1021/ja01553a042 | [General Description]
1,3-Dichloroisoquinoline undergoes Pd(PPh3)4 catalyzed regioselective coupling with arylboronic acids to afford to 1-aryl-3-chloroisoquinolines. Reaction of amine with 1,3-dichloroisoquinoline has been studied. Regioselectivity of the Stille coupling reaction of (1-ethoxyvinyl)tri(n-butyl)stannane with 1,3-dichloroisoquinoline has been investigated. |
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