| Identification | More | [Name]
QUININE SULFATE | [CAS]
804-63-7 | [Synonyms]
6-METHOXYCINCHONINE SULFATE
A-(6-METHOXY-4-QUINOLYL)-5-VINYL-2-QUINUCLIDINE-METHANOL SULFATE
QUININE BISULFATE
QUININE HEMISULFATE
QUININE SULFATE
QUININE SULPHATE
6’-methoxy-cinchonan-9-o(8alpha,9theta)-cinchonan-9-osulfate(2:1)(salt)
Cinchonan-9-ol,6’-methoxy-,(8.alpha.,9R)-,sulfate(2:1)(salt)
legatrin
quininehydrogensulfate
QuinineSulphate,>99%
Aflukin
Cinchonan-9-ol, 6'-methoxy-, (8a,9R)-, sulfate (2:1) (salt) (9CI)
Coco-Quinine
NSC 5362
Quinine, sulfate (2:1) (salt) (8CI)
Quinoc
QUININE SULPHATE 99%
Cinchonan-9-ol, 6'-methoxy-, (8α,9R)-, sulfate (2:1) (salt) | [EINECS(EC#)]
212-359-2 | [Molecular Formula]
C40H50N4O8S | [MDL Number]
MFCD00078499 | [Molecular Weight]
746.91 | [MOL File]
804-63-7.mol |
| Chemical Properties | Back Directory | [Melting point ]
235.2°C | [density ]
1.0807 (rough estimate) | [refractive index ]
1.6000 (estimate) | [form ]
Solid | [color ]
White to off-white | [Odor]
wh. fine needle-like cryst., odorless, very bitter taste | [BCS Class]
1 | [InChIKey]
AKYHKWQPZHDOBW-QJLYHTAINA-N | [SMILES]
O[C@@H](C1C=CN=C2C=CC(OC)=CC=12)[C@H]1C[C@]2(CCN1C[C@H]2C=C)[H].S(O)(O)(=O)=O |&1:1,14,16,21,r| | [LogP]
3.44 | [CAS DataBase Reference]
804-63-7(CAS DataBase Reference) | [EPA Substance Registry System]
Quinine sulfate (2:1) (804-63-7) |
| Safety Data | Back Directory | [Symbol(GHS) ]
GHS07 | [Signal word ]
Warning | [Hazard statements ]
H335-H319-H315 | [Precautionary statements ]
P264-P280-P302+P352-P321-P332+P313-P362-P264-P280-P305+P351+P338-P337+P313P | [Risk Statements ]
36/37/38 | [Safety Statements ]
26-36 | [RIDADR ]
1544 | [TSCA ]
TSCA listed | [HazardClass ]
6.1(b) | [PackingGroup ]
III | [HS Code ]
29339900 | [Safety Profile]
Human poison by ingestion. Human systemic effects by ingestion: acuity changes, blood agranulocytosis, fibrous hepatitis, flaccid paralysis without anesthesia, motor activity changes, mydriasis (pupillary dilation), nausea or vomiting, tinnitus, visual field changes. Experimental reproductive effects. Mutation data reported. When heated to decomposition it emits very toxic fumes of SO, and NO,. See also QUININE. |
| Hazard Information | Back Directory | [Chemical Properties]
White powder | [Uses]
ntimalarial. | [Uses]
Quinine, an extremely bitter substance, has been used by millions of malaria sufferers. In recent times, it has been employed successfully to treat chloroquine-resistant strains of P. falciparum but it frequently fails to provide a complete cure of the infection. | [Definition]
ChEBI: A organic sulfate salt obtained from guanethidine and sulfuric acid in a 2:1 ratio. | [Brand name]
Coco-Quinine (Lilly). | [World Health Organization (WHO)]
Quinine is an important drug in the treatment of multi- drugresistant
forms of malaria. Its use in nocturnal leg muscle cramps, a benign and
self-limiting condition, is connected with unjustified risks. Quinine is listed in the
WHO Model List of Essential Drugs for treatment of malaria. | [Purification Methods]
Crystallise it from water and dry it at 110o. [Beilstein 23 H 522, 23 I 168, 23 II 420, 23 III/IV 3269, 23 V 396.] |
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RYSS TECH LTD
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