| Identification | More | [Name]
S-2-Benzothiazolyl 2-amino-alpha-(methoxyimino)-4-thiazolethiolacetate | [CAS]
80756-85-0 | [Synonyms]
S-2-BENZATHIAZOYL-2-AMINO-ALPHA-METHOXYIMINO-4-THIAZOLACETAT
S-2-BENZOTHIAZOYL-2-AMINO-ALPHA-METHOXYIMINO-4-THIAZOLEACETATE
(2-mercaptobenzothiazolyl)-2-(2-aminothiazol-4-yl)-2-methoxyiminoacetate(syn
2-(2-amino-4-thiazole)-2-methoxyiminoacetic,thiobenzothiazoleester
2-(2-Amino-4-thiazolyl)-2-methoxyiminoacetic,thiobenzothiazoleester
2-amino-alpha-(methoxyimino)-4-thiazoleethanethioicacis-2-benzothiazolyl
s-2-benzothiazolyl(z)-2-amino-alpha-(methoxyimino)-4-thiazoleethanethioate
s-benzothiazol-2-yl(z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)thioacet
2-MERCAPTOBENZOTHIAZOLYL(Z)-2-AMINOTHIAZOLE-4-YL-2-METHOXY IMINO ACETATE(MAEM)
Ceftriaxone Sodium intermediate
S-benzothiazol-2-yl (Z)-2-(2-amino-1,3-thiazol-4-yl)-2-(methoxyimino)thioacetate
S-2-Benzothiazoyl-2-amino-alpha-methoxyimino-4-thiazoleacetate(MAEM)
S-2-benzothiazoyl-2-amino-α-methoxyimino-4-thiazoleacetate
(Benzothiazol-2-yl)-(Z)-2-methoxyimino-2-(2-amino-thiozol-4-yl) thioacetate
S-2-Benzothiazolyl-2-amino-alpha-(methoxyimino)-4-thiazolethioacetate
2-Mercaptobenzothiazolyl (2-Aminothiazolyl)-Methoxyimino Acetate
(BENZOTHIAZOL-2-YL)-2-(2-AMINOTHIZAZOL-4-YL)-(Z)-2-METHOXYIMINO THIOACETATE
2-Amino-α-(methoxyimino)-4-thiazoleethanethioic acid, S-2-benzothiazolyl ester
S-(Benzothiazol-2-yl) (Z)-(2-aminothiazol-4-yl) (methoxyimino) thioacetate
S-(Benzothiazol-2-yl) 2-amino-α-(methoxyimino) thiazole-4-thioacetate | [EINECS(EC#)]
279-540-6 | [Molecular Formula]
C13H10N4O2S3 | [MDL Number]
MFCD00134182 | [Molecular Weight]
350.44 | [MOL File]
80756-85-0.mol |
| Chemical Properties | Back Directory | [Appearance]
light yellow powder | [Melting point ]
128-130 °C(lit.)
| [Boiling point ]
563.2±42.0 °C(Predicted) | [density ]
1.63 | [refractive index ]
1.6200 (estimate) | [storage temp. ]
Refrigerator, Under Inert Atmosphere | [solubility ]
Chloroform (Slightly), Methanol (Slightly) | [form ]
Solid | [pka]
1.22±0.10(Predicted) | [color ]
Pale Yellow | [Stability:]
Moisture Sensitive | [Major Application]
pharmaceutical small molecule | [InChI]
InChI=1S/C13H10N4O2S3/c1-19-17-10(8-6-20-12(14)15-8)11(18)22-13-16-7-4-2-3-5-9(7)21-13/h2-6H,1H3,(H2,14,15)/b17-10- | [InChIKey]
COFDRZLHVALCDU-YVLHZVERSA-N | [SMILES]
S(C1SC2C=CC=CC=2N=1)C(=O)/C(/C1N=C(N)SC=1)=N\OC | [CAS DataBase Reference]
80756-85-0(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xi | [Risk Statements ]
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice .
S37/39:Wear suitable gloves and eye/face protection . | [WGK Germany ]
2
| [RTECS ]
XJ4664500
| [HS Code ]
2934.20.8000 |
| Hazard Information | Back Directory | [Hazard]
Low toxicity by ingestion. | [Chemical Properties]
S-2-Benzothiazolyl 2-amino-alpha-(methoxyimino)-4-thiazolethiolacetate is light yellow powder
| [Uses]
S-2-Benzothiazolyl 2-amino-alpha-(methoxyimino)-4-thiazolethiolacetate is used in the synthesis of Cefotaxime and related derivatives, such as: Ceftriaxone (C245000).
| [Synthesis]
In a 500 ml four-necked flask equipped with mechanical stirring, constant pressure dropping funnel, reflux condenser and thermometer, 20 g (0.0995 mol) of aminothiazoleacetic acid was added, dibenzothiazole sulfide, pyridine and 100 ml of dichloromethane |
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