| Identification | More | [Name]
BENZYL 2,2,2-TRICHLOROACETIMIDATE | [CAS]
81927-55-1 | [Synonyms]
2,2,2-TRICHLOROACETIMIDIC ACID BENZYL ESTER
BENZYL 2,2,2-TRICHLOROACETIMIDATE
LABOTEST-BB LT00455324
TRICHLOROACETIMIDIC ACID BENZYL ESTER
Benzyl 2,2,2-trichloroethanimidoate
Benzyl trichloroacetimidate
Benzyl 2,2,2-trichloroacetimidate, 98+%
Ethanimidic acid, 2,2,2-trichloro-, phenylmethyl ester
Benzyl 2,2,2-trichloroacetimidate, GC 99%
BENZYLPHOSPONIC ACID
Benzyl 2,2,2-trichloroacetimidate, 99 % | [Molecular Formula]
C9H8Cl3NO | [MDL Number]
MFCD00000805 | [Molecular Weight]
252.52 | [MOL File]
81927-55-1.mol |
| Chemical Properties | Back Directory | [Appearance]
clear colorless to yellow liquid | [Melting point ]
3 °C | [Boiling point ]
106-114 °C0.5 mm Hg(lit.) | [density ]
1.359 g/mL at 25 °C(lit.)
| [refractive index ]
n20/D 1.545(lit.)
| [Fp ]
>230 °F
| [storage temp. ]
2-8°C
| [solubility ]
Miscible with cyclohexane/dichloromethane. | [form ]
Liquid | [pka]
2.23±0.70(Predicted) | [color ]
Clear colorless to yellow | [Sensitive ]
Moisture Sensitive | [BRN ]
2525375 | [CAS DataBase Reference]
81927-55-1(CAS DataBase Reference) |
| Safety Data | Back Directory | [Hazard Codes ]
Xn | [Risk Statements ]
R22:Harmful if swallowed.
R36/37/38:Irritating to eyes, respiratory system and skin . | [Safety Statements ]
S26:In case of contact with eyes, rinse immediately with plenty of water and seek medical advice . | [WGK Germany ]
3
| [F ]
8-10-21 | [HS Code ]
29252900 |
| Hazard Information | Back Directory | [Chemical Properties]
clear colorless to yellow liquid | [Uses]
Benzyl 2,2,2-trichloroacetimidate was used as reagent during the synthesis of funiculosin dimethyl ether and (S)-3-(benzyloxy)-2-methylpropanal. It was used in the acid-catalyzed benzylation of hydroxy groups. | [Uses]
Benzyl 2,2,2-trichloroacetimidate is used for the acid-catalyzed benzylation of hydroxy groups. It acts as reagent during the synthesis of funiculosin dimethyl ether and (S)-3-(benzyloxy)-2-methylpropanal. It can also be used for mild esterification of carboxylic acids in the presence of a catalytic amount of BF3 etherate. | [Uses]
Benzyl 2,2,2-trichloroacetimidate is used for the acid-catalyzed benzylation of hydroxy groups.
| [Purification Methods]
Purify the imidate by distillation to remove up to 1% of PhCH2OH as stabiliser. A solution in hexane can be stored for up to 2 months without decomposition. It is hygroscopic and has to be stored dry. [Wessel et al. J Chem Soc, Perkin Trans 1 2247 1985, Beilstein 6 IV 2265.] |
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