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107-07-3 Structure

107-07-3 Structure



AKOS BBS-00004331
2-Chloroethyl alcohol
2-Hydroxyethyl chloride

[Molecular Formula]

[MDL Number]

[Molecular Weight]

[MOL File]

Chemical PropertiesBack Directory

Ethylene chlorohydrine is a clear, colourless liquid with mild, ethereal odour. It reacts with alkali metals. Ethylene chlorohydrine has applications as a laboratory reagent and as a pharmaceutical intermediate. Ethylene chlorohydrine is a building block in the production of pharmaceuticals, biocides, and plasticisers, used for manufacture of thiodiglycol, an important solvent for cellulose acetate and ethyl cellulose, textile-printing dyes, extraction of pine lignin, in dewaxing, refining of rosin, and the cleaning of machines. Several dyes are prepared by the alkylation of aniline derivatives with chloroethanol.

colourless liquid

Ethylene chlorohydrin is a colorless liquid with a faint, ethereal odor.
[mp ]

-63 °C
[bp ]

129 °C(lit.)
[density ]

1.201 g/mL at 25 °C(lit.)
[vapor density ]

2.78 (vs air)
[vapor pressure ]

5 mm Hg ( 20 °C)
[refractive index ]

n20/D 1.441(lit.)
[Fp ]

140 °F
[storage temp. ]


Stable. Incompatible with oxidizing agents.
[Water Solubility ]

[Sensitive ]

Moisture Sensitive
[Merck ]

[BRN ]

[CAS DataBase Reference]

107-07-3(CAS DataBase Reference)
[NIST Chemistry Reference]

Ethanol, 2-chloro-(107-07-3)
[EPA Substance Registry System]

107-07-3(EPA Substance)
Safety DataBack Directory
[Hazard Codes ]

[Risk Statements ]

R26/27/28:Very Toxic by inhalation, in contact with skin and if swallowed .
R39/23/24/25:Toxic: danger of very serious irreversible effects through inhalation, in contact with skin and if swallowed .
R23/24/25:Toxic by inhalation, in contact with skin and if swallowed .
R11:Highly Flammable.
[Safety Statements ]

S28:After contact with skin, wash immediately with plenty of ... (to be specified by the manufacturer) .
S45:In case of accident or if you feel unwell, seek medical advice immediately (show label where possible) .
S7/9:Keep container tightly closed and in a well-ventilated place .
S36/37:Wear suitable protective clothing and gloves .
S16:Keep away from sources of ignition-No smoking .
S7:Keep container tightly closed .

UN 1135 6.1/PG 1
[WGK Germany ]


[F ]

[HazardClass ]

[PackingGroup ]

[HS Code ]

[Safety Profile]

: A poison by ingestion, inhalation, skin contact, intraperitoneal, intravenous, and subcutaneous routes. Moderately toxic to humans by inhalation. It can affect the nervous system, liver, spleen, and lungs. An experimental teratogen. Mutation data reported. A severe eye and mild skin irritant. Flammable liquid when exposed to heat, flame, or oxidizers. To fight fire, use alcohol foam, CO2, dry chemical. Violent reaction with chlorosulfonic acid, ethylene hamine, sodmm hydroxide. Reacts with water or steam to produce toxic and corrosive fumes. Potentially violent reaction with oxidizing materials. When heated to decomposition it emits highly toxic fumes of Cland phosgene. See also CHLORINATED HYDROCARBONS, ALIPHATIC.
[Hazardous Substances Data]

107-07-3(Hazardous Substances Data)
Raw materials And Preparation ProductsBack Directory
【Raw materials】

Hydrochloric acid-->ETHYLENE OXIDE-->Sulfur dichloride-->hypochlorous acid
【Preparation Products】

N-[2-(4-Bromophenoxy)ethyl]pyrrolidine-->Choline chloride-->Choline hydroxide-->3-Hydroxypropionitrile-->1-(2-Chloroethyl)pyrrolidine Hydrochloride-->(2-MORPHOLIN-4-YL-ETHYL)-HYDRAZINE-->(2-PYRROLIDIN-1-YL-ETHYL)-HYDRAZINE-->1-(2-Aminoethyl)pyrrolidine-->1-(2-PYRROLIDINOETHYL)PIPERAZINE-->fluorescent brightener 311-->1,4-BIS(2-HYDROXYETHYL)PIPERAZINE-->2-Mercaptoethanol-->Tris(2-chloroethyl) phosphate-->4-(2-(N-BENZYL-N-METHYLAMINO)ETHOXY)-3,5-DICHLOROBENZENAMINE-->2,2'-Thiodiethanol-->2-(METHYLTHIO)ETHANOL-->2-Hydroxyethyl methacrylate-->4-((4-BENZYLMORPHOLIN-2-YL)METHOXY)-3,5-DICHLOROBENZENAMINE-->4-(2-Hydroxyethoxy)benzaldehyde-->Acetylcholine chloride-->4-(2-MORPHOLINOETHOXY)-3,5-DICHLOROBENZENAMINE-->N-(2-Hydroxyethyl)-N-methylaniline-->bis(2-phenoxyethyl) peroxydicarbonate-->CLOPERASTINE-->(4-CHLORODIPHENYL)METHYL BETA-CHLOROETHYL ETHER-->2-(2,4,6-TRICHLORO PHENOXY)CHLOROETHANE-->Carbachol-->Ethyl 2-hydroxyethyl sulfide-->BENZHYDRYL B-CHLOROETHYL ETHER-->chloroalcohol type homogeneous strongly basic anion exchange membrane-->2-Chloroethyl chloroformate-->2-Fluoroethanol-->ETHYL 2-CHLOROETHYLCARBAMATE-->Diphenhydramine-->2-Fluoroethyl bromide-->1-Bromo-2-chloroethane-->2-CHLOROETHYL P-TOLUENESULFONATE-->Adefovir dipivoxil-->2-Iodoethanol-->Troxerutin
Hazard InformationBack Directory
[General Description]

ETHYLENE CHLOROHYDRIN(107-07-3) is a colorless liquid with an ether-like odor. ETHYLENE CHLOROHYDRIN(107-07-3) is soluble in water and is also a combustible liquid. Its vapors are heavier than air and ETHYLENE CHLOROHYDRIN(107-07-3) is very toxic by inhalation and skin absorption. Prolonged exposure to low concentrations or short term exposure to high concentrations may result in adverse health effects.
[Reactivity Profile]

Mixing ethylene chlorohydrin in equal molar portions with any of the following substances in a closed container caused the temperature and pressure to increase: chlorosulfonic acid, ethylene diamine, and sodium hydroxide, [NFPA 1991]. Ethylenediamine reacts violently with ethylene chlorohydrin. (Lewis, R.J., Sr. 1992. Sax's Dangerous Properties of Industrial Materials, 8th Edition. New York: Van Nostrand Reinhold. pp. 1554.).
[Air & Water Reactions]

Highly flammable. ETHYLENE CHLOROHYDRIN is soluble in water.

Deadly via ingestion, inhalation, and skin absorption; strong irritant, penetrates ordinary rubber gloves and protective clothing. Moderate fire hazard. Questionable carcinogen.
[Health Hazard]

Very toxic; probable oral lethal dose in humans is 50-500 mg/kg or between 1 teaspoon and 1 ounce for a 70 kg (150 lb.) person. Poisoning causes liver and kidney degeneration and irritates mucous membranes; it may be cumulative. Several fatal cases with brain edema and lung edema have been reported from industrial exposure by inhalation and skin contact. It is more toxic by skin contact than orally.
[Potential Exposure]

Ethylene chlorohydrin is used as a solvent and emulsifier; in the synthesis of ethylene glycol, ethylene oxide, amines, carbitols, indigo, malonic acid, novocaine, and in other reactions where the hydroxyethyl group is introduced into organic compounds; for the separation of butadiene from hydrocarbon mixtures; in dewaxing and removing cycloalkanes from mineral oil; in the refining of rosin; in the manufacture of certain pesticides and in the extraction of pine lignin. In the lacquer industry, it is used as a solvent for cellulose acetate, cellulose esters, resins and waxes; and in the dyeing and cleaning industry, it is used to remove tar spots; as a cleaning agent for machines; and as a solvent in fabric dyeing. It has also found use in agriculture in speeding up sprouting of potatoes and in treating seeds to inhibit biological activity. Making chemical warfare agents
[Fire Hazard]

ETHYLENE CHLOROHYDRIN decomposition products will react with water or steam to produce toxic and corrosive fumes of phosgene and hydrogen chloride. Vapors are heavier than air and may flash back to a source of ignition.
[First aid]

If this chemical gets into the eyes, remove any contact lenses at once and irrigate immediately for at least 15 minutes, occasionally lifting upper and lower lids. Seek medical attention immediately. If this chemical contacts the skin, remove contaminated clothing and wash immediately with soap and water. Seek medical attention immediately. If this chemical has been inhaled, remove from exposure, begin rescue breathing (using universal precautions, including resuscitation mask) if breathing has stopped and CPR if heart action has stopped. Transfer promptly to a medical facility. When this chemical has been swallowed, get medical attention. Give large quantities of water and induce vomiting. Do not make an unconscious person vomit. Medical observation is recommended for 24 to 48 hours after breathing overexposure, as pulmonary edema may be delayed. As first aid for pulmonary edema, a doctor or authorized paramedic may consider administering a drug or other inhalation therapy.

UN1135 Ethylene chlorohydrin, Hazard class: 6.1; Labels: 6.1-Poison Inhalation Hazard, 3-Flammable liquid, Inhalation Hazard Zone B

May form explosive mixture with air. Strong oxidizers may cause fire and explosions. Incompatible with strong caustics (formation of ethylene gas), strong acids; alkaline metals; aliphatic amines; isocyanates. Violent reaction with ethylene diamine, chlorosulfonic acid. Attacks some plastics, rubber and coatings. Reacts with water or steam producing toxic and corrosive fumes
[Waste Disposal]

Incineration, preferably after mixing with another combustible fuel. Care must be exercised to assure complete combustion to prevent the formation of phosgene. An acid scrubber is necessary to remove the halo acids produced.
Material Safety Data Sheet(MSDS)Back Directory
[msds information]

Ethylene chlorohydrin(107-07-3).msds
Spectrum DetailBack Directory
[Spectrum Detail]

Well-known Reagent Company Product InformationBack Directory
[Acros Organics]

2-Chloroethanol, 99+%(107-07-3)
[Alfa Aesar]

2-Chloroethanol, 99%(107-07-3)
[Sigma Aldrich]

107-07-3 suppliers list
Tags:107-07-3 Related Product Information
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